IGLabel

This package provides and easy way to label your IG and T-cell receptor sequences according to the IMGT standard.

Installation

pip install iglabel

Usage

from iglabel import *

label_dict, position_dict = IMGT(["CASSLGTGELFF"], ["CDR3"])

INPUTS

• sequences: A list of sequences for which you want to obtain the IMGT labels.
• regions: A list of regions in the same order as the sequences to receive the right labelling. Possible regions are: FR1, CDR1, FR2, CDR2, FR3, CDR3, FR4.
• save: If True, a txt document will be saved in the current directory. If False, no document will be saved.

RETURN

• label_dict: Contains the sequences per region as keys and the corresponding IMGT labels as values.

• position_dict: Contains the IMGT labels as keys and the positions from n-lengthsequence as values.

• A txt document which visualizes the sequence with the corresponding IMGT label.

Example: Multiple Sequences

You can parse multiple sequences at once if you want:

label_dict, position_dict = IMGT(["CASSLGTG", "CASSLGTGELFF"], ["CDR2", "CDR3"], save = False)

Citation

If you use this package, please cite the following paper:

Lefranc MP, Pommié C, Ruiz M, Giudicelli V, Foulquier E, Truong L, Thouvenin-Contet V, Lefranc G. IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains. Dev Comp Immunol. 2003 Jan;27(1):55-77. doi: 10.1016/s0145-305x(02)00039-3. PMID: 12477501.