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Project description
Electrophysiological Cancer Cell Model
Attempt to model an A549 cancer cell's ion channels using an HMM (Hidden Markov Model) and simulation of voltage + current development accross the membrane of the cell.
This software comes in three flavours:
- to run the
main.rs
simulation, docargo run
, - to compile the Python module, do
maturin develop --features pyo3
, - to precompile for the Astro dashboard, do
yarn run wasm-pack build frontend
.
A visual to capture your interest:
(Image source: here).
This computational model is based on Langthaler et al., 2021: A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma.
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