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ISEQcBioPortal

Scripts that allow you to:

  1. Create/Update database from cBioPortal
  2. Annotate VCF with information such as:
  • number of samples with one or more mutations
  • percentage of samples with one or more mutations

Install iseqcbioportal library

Optional steps (create virtual environment):

python3 -m venv venv
source venv/bin/activate

Obligatory steps:

python3 -m pip install --upgrade pip
pip3 install iseqcbioportal

Requirements

  • python >=3.6
  • pandas >= 1.4.2
  • requests >= 2.28.1
  • SQLAlchemy >= 1.4.0
  • loguru >= 0.6.0
  • pysam >= 0.21.0

Create databases

create_cbioportal_database

Annotate VCF

vcf_annotate_cbioportal --input-vcf "/path/to/input.vcf.gz" \
                        --studies "studyId" \
                        --output-vcf "/path/to/output.vcf.gz"

Metadata

Release files for iseqcbioportal 0.0.6

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Source distribution for iseqcbioportal 0.0.6
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