pyhdx 0.4.3

Derive ΔG for single residues from HDX-MS data

PyHDX

PyHDX is python project which can be used to derive Gibbs free energy from HDX-MS data.

PyHDX stable documentation

PyHDX on YouTube

Installation

Installation of the latest stable beta with pip:

$ pip install pyhdx

Installation with web interface extra:

$ pip install pyhdx[web]

Conda install (includes web interface extra):

$ conda install pyhdx

Run PyHDX

Most up-to-date code examples are in the directory pyhdx/templates

To run the web server:

$ pyhdx serve

Please refer to the docs for more details on how to run PyHDX.

Web Application

The PyHDX web application is currently hosted at: http://pyhdx.jhsmit.org

A test file can be downloaded from here and here (right click, save as).

A beta version might be available at: http://pyhdx-beta.jhsmit.org

The latest beta docs are found here

Publication

Our Analytical Chemistry Publication describing PyHDX can be found here

The latest version (v2) of our biorxiv paper: https://doi.org/10.1101/2020.09.30.320887

Python code for analysis and generation the figures in the paper are here: https://github.com/Jhsmit/PyHDX-paper

Other

HDX MS datasets repository and format (alpha): https://github.com/Jhsmit/HDX-MS-datasets

HDXMS datasets python bindings: https://github.com/Jhsmit/hdxms-datasets