metabolic modeling package
Project description
ReFramed: metabolic modeling package
ReFramed implements many constraint-based simulation methods (see list below), and contains interfaces to other libraries of the COBRA ecosystem including escher, cobrapy, and optlang.
Available methods
Name |
Long name |
Reference |
---|---|---|
FBA |
Flux Balance Analysis |
(Varma and Palsson, 1993) |
FVA |
Flux Variability Analysis |
(Mahadevan and Schilling, 2003) |
pFBA |
Parsimonious FBA |
(Lewis et al, 2010) |
FBrAtio |
FBA with flux ratios |
(Yen et al, 2013) |
CAFBA |
Constrained Allocation FBA |
(Mori et al, 2016) |
MOMA |
Minimization of Metabolic Adjustment |
(Segre et al, 2002) |
lMOMA |
linear MOMA |
(Segre et al, 2002) |
ROOM |
Regulatory On/Off Minimization |
(Shlomi et al, 2005) |
ll-FBA |
loopless FBA |
(Schellenberger et al, 2011) |
TFA |
Thermodynamic Flux Analysis |
(Henry et al, 2007) |
TVA |
Thermodynamic Variability Analysis |
(Henry et al, 2007) |
NET |
Network-embedded thermodynamic analysis |
(Kummel et al 2006) |
GIMME |
Gene Inactivity Moderated by Met and Exp |
(Becker and Palsson, 2008) |
E-Flux |
E-Flux |
(Colijn et al, 2009) |
SteadyCom |
Community simulation |
(Chan et al, 2017) |
Credits and License
Developed by Daniel Machado at the European Molecular Biology Laboratory (2019).
ReFramed is a refactored version of the framed library.
Released under an Apache License.
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