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REvolutionH-tl: Reconstruction of Evolutionary Histories tool

Project description

REvolutionH-tl logo.

Bioinformatics tool for the reconstruction of evolutionary histories. Input: fasta files or sequence alignment hits, Output: orthology. event-labeled gene trees, and reconciliations.

Bioinformatics & complex networks lab

Steps

  1. Orthogroup & best hit selection. Input: alignment hits (generate this using revolutionhtl.diamond) .
  2. Orthology and gene tree reconstruction. Input: best hits (generate this at step 1).
  3. Species tree reconstruction. Input: gene trees (generate this at step 2).
  4. Tree reconciliation. Input: gene and species trees (generate this at steps 2 and 3).

Install

pip install revolutionhtl

Requirements

Python >=3.7

If you want to run sequence alignments using revolutionhtl, then install Diamond.

Usage

Go to the wiki for details and an example.

python -m revolutionhtl <arguments>

The arguments specify steps to run and parameters.

Specify steps and input data (Click to expand) - -h --help show this help message and exit
-steps [int ...] List of steps to run (default: 1 2 3 4).
--- pipeline

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