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A sophisticated framework for bidirectional cross-modality translation between scRNA-seq and scDNAm profiles with broad biological applicability. We show that scBOND accurately translates data while preserving biologically significant differences between closely related cell types. It also recovers functional and tissue-specific signals in the human brain and reveals stage-specific and cell type-specific transcriptional-epigenetic mechanisms in the oligodendrocyte lineage.

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Release files for scBond 1.0

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Source distribution for scBond 1.0
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scbond-1.0.tar.gz 28.7 kB Details

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scbond-1.0-py3-none-any.whl Python 3 none any Details

Total release size: 57.4 kB

Release files / scbond-1.0.tar.gz

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Release files / scbond-1.0-py3-none-any.whl

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