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    # TrialBench: Multi-modal AI-ready Clinical Trial Datasets
    
    [![PyPI version](https://pypi-camo.freetls.fastly.net/1084b9f2f9dfb3ed603718f4160bbbce019cb759/68747470733a2f2f696d672e736869656c64732e696f2f707970692f762f747269616c62656e63682e7376673f636f6c6f723d627269676874677265656e)](https://pypi.org/project/trialbench/)
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    ## 1. Installation
    
    ```bash
    pip install trialbench
    ```
    
    ## 2. Tasks & Phases
    
    | Supported Tasks              | Task Name                                            | Phase Name |
    | ---------------------------- | ---------------------------------------------------- | ---------- |
    | Mortality Prediction         | `mortality_rate`/`mortality_rate_yn`             | 1-4        |
    | Adverse Event Prediction     | `serious_adverse_rate`/`serious_adverse_rate_yn` | 1-4        |
    | Patient Retention Prediction | `patient_dropout_rate`/`patient_dropout_rate_yn` | 1-4        |
    | Trial Duration Prediction    | `duration`                                         | 1-4        |
    | Trial Outcome Prediction     | `outcome`                                          | 1-4        |
    | Trial Failure Analysis       | `failure_reason`                                   | 1-4        |
    | Dosage Prediction            | `dose`/`dose_cls`                                | All        |
    
    ### Clinical Trial Phases
    
    ```
    Phase 1: Safety Evaluation
    Phase 2: Efficacy Assessment
    Phase 3: Large-scale Testing
    Phase 4: Post-marketing Surveillance
    ```
    
    ## 3. Quick Start
    
    ### 3.1 Usage of `trialbench`
    
    ```python
    import trialbench
    
    # Download all datasets at once (optional)
    save_path = 'data/'
    trialbench.function.download_all_data(save_path)
    
    # Load dataset
    task = 'dose'
    phase = 'All'
    
    # Load dataloader.Dataloader 
    train_loader, valid_loader, test_loader, num_classes, tabular_input_dim = trialbench.function.load_data(task, phase, data_format='dl')
    # or Load pd.Dataframe
    train_df, valid_df, test_df, num_classes, tabular_input_dim = trialbench.function.load_data(task, phase, data_format='df')
    ```
    
    ### 3.2 Attributes of Each Task
    
    Each task provides different feature sets. The Dosage Prediction task returns `nctid_lst`, `smiles_lst`, and `mesh_lst`, while all other tasks provide `nctid_lst`, `icdcode_lst`, `smiles_lst`, `criteria_lst`, `tabular_lst`, `text_lst`, and `mesh_lst`.
    
    All tasks use `label_lst` as the label variable. Please refer to the guide documentation for detailed feature as well as label descriptions.
    
    ```python
    # Demo for accessing data elements
    task = 'dose'
    phase = 'All'
    
    # When using DataLoader objects:
    # Features
    nctid_list = train_loader.dataset.nctid_lst
    smiles_list = train_loader.dataset.smiles_lst
    mesh_list = train_loader.dataset.mesh_lst
    # Labels
    # return [datatset_name, label_max, label_min, label_avg], e.g. ['NCT03422510', 2, 2, 2]
    label_list = train_loader.dataset.label_lst 
    
    # When using DataFrames:
    # Features
    nctid_list = train_df.nctid_lst
    smiles_list = train_df.smiles_lst
    mesh_list = train_df.mesh_lst
    # Labels
    label_list = train_df.label_lst
    ```
    
    ## 4. Data Loading
    
    ### `load_data` Parameters
    
    | Parameter       | Type | Description                                              |
    | --------------- | ---- | -------------------------------------------------------- |
    | `task`        | str  | Target prediction task (e.g., 'mortality_rate_yn')       |
    | `phase`       | int  | Clinical trial phase (1-4)                               |
    | `data_format` | str  | Data format ('dl' for Dataloader, 'df' for pd.DataFrame) |
    
    ## 5. Citation
    
    If you use TrialBench in your research, please cite:
    
    ```bibtex
    @article{chen2024trialbench,
      title={Trialbench: Multi-modal artificial intelligence-ready clinical trial datasets},
      author={Chen, Jintai and Hu, Yaojun and Wang, Yue and Lu, Yingzhou and Cao, Xu and Lin, Miao and Xu, Hongxia and Wu, Jian and Xiao, Cao and Sun, Jimeng and others},
      journal={arXiv preprint arXiv:2407.00631},
      year={2024}
    }
    ```

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