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BiNgo Genome Viewer — a lightweight browser-based genomics viewer

Project description

BiNgo Genome Viewer

A lightweight, browser-based genomics viewer for visualizing genomes, coverage tracks, read alignments, variants, and annotations. Built as a modern alternative to IGV.

Supported File Formats

Type Formats
Genome GenBank (.gb, .gbk), FASTA (.fasta, .fa)
Coverage BigWig (.bw), WIG (.wig), BedGraph (.bedgraph, .bdg)
Reads BAM (.bam + .bai index)
Variants VCF (.vcf, .vcf.gz)
Annotations BED (.bed), GFF (.gff, .gff3), GTF (.gtf), GenBank (.gb)

Quick Start

Requires Python 3.10 or newer. Download from python.org if needed.

Install with pip (recommended)

No Node.js required — the frontend is pre-built and bundled.

pip install BiNgoViewer
bingo

Options:

bingo --port 9000        # use a custom port
bingo --no-browser       # start without opening the browser
bingo --install          # create a desktop shortcut

Windows (one-click)

Double-click Install_Windows.bat. It will install Python dependencies into a local environment and launch the viewer. No command line needed.

macOS / Linux (one-click)

Double-click Install_macOS.command (or run it from a terminal). It will create a virtual environment, install dependencies, and launch the viewer.

Permission denied? Run once in Terminal:

chmod +x Install_macOS.command

Docker

No Python or Node.js required — everything runs inside the container.

cd app
docker compose up --build

Then open http://localhost:8000.

Troubleshooting

Problem Solution
python not found Install Python 3.10+ and check Add to PATH during setup
pip install fails Try pip install --user BiNgoViewer or use a virtual environment
Port 8000 in use Run bingo --port 9000 (or any free port)
Browser doesn't open Visit http://localhost:8000 manually
Server won't stop The server auto-exits when you close all browser tabs; or press Ctrl+C

Usage

  1. Load files — Use the file picker or drag and drop. Genome and track files are auto-classified by extension.
  2. Navigate — Click and drag on tracks to pan; scroll wheel to zoom; use the coordinate bar to jump to a region.
  3. Track settings — Click the gear icon to adjust height, color, scale, and bar width.
  4. Reorder tracks — Drag the grip handle on any track label.
  5. Export — Save the current view as SVG or PNG.
  6. Save session — Store your workspace and restore it later.

Project Structure

├── Install_Windows.bat         # Windows installer (double-click)
├── Install_macOS.command       # macOS / Linux installer (double-click)
├── README.md
├── pyproject.toml              # pip package definition
├── bingoviewer/                # Installable Python package
│   ├── cli.py                  # `bingo` CLI entry point
│   ├── server/                 # FastAPI backend (bundled)
│   └── frontend_dist/          # Pre-built React frontend
└── app/                        # Application source code
    ├── backend/                # Python (FastAPI) REST API
    └── frontend/               # React (Vite) user interface

Citation

If you use this software in your research, please cite:

Ngo, B.M. (2026). BiNgo Genome Viewer (v1.8.2) [Software].

References & Acknowledgments

Click to expand

Software Dependencies

Backend

  • FastAPI — Ramírez, S. (2018). FastAPI: A modern, fast web framework for building APIs with Python. https://fastapi.tiangolo.com/
  • Uvicorn — Encode OSS. ASGI server implementation for Python. https://www.uvicorn.org/
  • BioPython — Cock, P.J.A. et al. (2009). Biopython: freely available Python tools for computational molecular biology and bioinformatics. Bioinformatics, 25(11), 1422–1423.
  • pyfaidx — Shirley, M.D. et al. (2015). Efficient "pythonic" access to FASTA files using pyfaidx. PeerJ PrePrints, 3:e1196.
  • bamnostic — Sherman, M.A. & Mills, R.E. (2019). BAMnostic: a pure Python, OS-agnostic Binary Alignment Map (BAM) file parser and random access tool.

Frontend

File Format Specifications

  • SAM/BAM — Li, H. et al. (2009). The Sequence Alignment/Map format and SAMtools. Bioinformatics, 25(16), 2078–2079.
  • VCF — Danecek, P. et al. (2011). The variant call format and VCFtools. Bioinformatics, 27(15), 2156–2158.
  • BigWig/WIG — Kent, W.J. et al. (2010). BigWig and BigBed: enabling browsing of large distributed datasets. Bioinformatics, 26(17), 2204–2207.
  • BED — UCSC Genome Browser, University of California, Santa Cruz.
  • GFF3 — Sequence Ontology Project. Generic Feature Format Version 3.
  • GTF — Ensembl genome database project.
  • GenBank — Benson, D.A. et al. (2013). GenBank. Nucleic Acids Research, 41(D1), D36–D42.

Inspiration

  • IGV — Robinson, J.T. et al. (2011). Integrative Genomics Viewer. Nature Biotechnology, 29(1), 24–26.

Acknowledgments

Early version testing and feedback:

  • Amanda Antoch
  • Isaac Poarch
  • Otto Chipashvili
  • Jake Colautti

License

All rights reserved. Contact the author for licensing inquiries.

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