GFHunter is a long read sequence transcriptome alignment-based fusion genes detection tool.
Project description
GFHunter is a long read sequence transcriptome alignment-based fusion genes detection tool.
Indexing: User can download the prepared index folder based on GENCODE release 44 here or create a new index by GFHunter index function.
Detection: GFHunter detects fusions in long read RNA-seq data, user just need index folder and long read data under detection.
Benchmark evaluations position GFHunter as redefining the analytical frontiers of gene fusion detection: 1. Lowest false-positive fusion rates in non-tumor data. 2. Achieves a substantially higher F1-score in real cancer cell lines evaluation. 3. Operates many times faster and requires fewer and stable memory than other tools.
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