Tools for analyzing force spectroscopy data.
What it is
It is a software for the (semiautomatic) analysis and filtering of force curves. Force curves are the output of an analytical technique called force spectroscopy. A force spectroscopy experiment usually requires the analysis of thousands of force curves at a time. As of today, there is no standard, free software for the analysis of force curves. Hooke aims to solve that.
What it does
- View, annotate, measure force curves
- Worm-like chain and freely-jointed chain fit of force peaks
- Automatic convolution-based filtering of empty curves
- Automatic fit and measurement of multiple force peaks
- Handles force-clamp force experiments (experimental)
- It is extensible by users by mean of plugins and drivers
See Hooke’s Google Code homepage for more details.
How it works
See the doc/tutorial.txt file distributed with Hooke, or the online docs.
Where it’s published
Sandal M, Benedetti F, Brucale M, Gomez-Casado A, Samorì B. “Hooke: an open software platform for force spectroscopy.” Bioinformatics, 2009 25(11):1428-1430. doi:10.1093/bioinformatics/btp180
Please cite Hooke if you use it.
If you have troubles in using it, before throwing it in the trash:
Remember that Hooke is still experimental software! It has been mostly done to fit the needs of its authors, and there is no guarantee it will do what you need. However, you can write us/help us improve it so that it does. We aim to make of Hooke a robust tool that can help your research.
Hooke is available as a Git repository:
$ git clone git://tremily.us/hooke.git
See the docs for installation details.
Hooke is released under the GNU Lesser General Public License, either version 3 of the License (COPYING and COPYING.LESSER), or (at your option) any later version.