JwzTumor 0.1.12

Breast ultrasound benign-malignant diagnosis with segmentation-assisted multi-task learning.

JwzTumor

Breast ultrasound benign-malignant diagnosis with segmentation-assisted multi-task learning.

Overview

JwzTumor implements LABDG-Pre + DGBC-MTLNet + MPTC-Head, a multi-task system for breast tumor diagnosis from ultrasound images:

• LABDG-Pre: Lesion-aware boundary-preserving domain-generalized preprocessing
• DGBC-MTLNet: Domain-generalized boundary-context collaborative multi-task network (CNN-Mamba hybrid)
• MPTC-Head: Morphology-prompted topology-consistent classification head (4-stream)

The system outputs: classification probability, segmentation mask, edge map, SDM, uncertainty map, and explainability visualizations.

Project Structure

jwz-tumor/
  pyproject.toml
  configs/          # 8 YAML configs
  dataset/          # BUSBRA + BUSI data
  web/              # React + Vite + TypeScript frontend source
  scripts/          # Frontend packaging and maintenance scripts
  src/JwzTumor/
    cli/            # CLI entrypoints, including jwzt server
    data/           # Datasets, preprocessing, augmentation, cache, audit, collate
    models/         # LABDG-Pre, DGBCEncoder, MPP, decoder, MPTC-Head
    losses/         # 7 loss modules + factory
    training/       # Stage trainer, scheduler, callbacks
    inference/      # Predictor, TTA, postprocessing, visualization
    evaluation/     # Classification + segmentation metrics
    server/         # FastAPI inference server, /api/report, packaged static UI
      report/       # Rule/LLM/hybrid report generation
      ui/           # Built frontend files served by jwzt server --with-ui
    utils/          # Config, seed, logging, I/O, registry
  tests/            # Python tests

Datasets

BUSBRA (Training)

• Images: bus_{id}-{side}.png, Masks: mask_{id}-{side}.png
• Labels: bus_data.csv (Pathology: benign/malignant)
• CV: 5-fold-cv.csv or 10-fold-cv.csv
• Case-level splitting (no leak)

BUSI (Testing)

• Directory-based: benign/, malignant/
• Skip: normal-不使用/
• Multi-mask: OR union in original size before resize
• RGB images converted to grayscale

Installation

# Install from PyPI
pip install JwzTumor

# Using uv
uv pip install -e .

# Development
uv pip install -e ".[dev]"

Quick Start

# Show version
jwzt version

# Export config template
jwzt get --name train_full --output configs/my_config.yaml

# Train
jwzt train --config configs/train_full.yaml --experiment-name exp001 --fold 1

# Stage-specific training
jwzt train --config configs/train_pretrain_pre.yaml --stage pretrain_pre --fold 1
jwzt train --config configs/train_pretrain_seg.yaml --stage pretrain_seg --fold 1
jwzt train --config configs/train_cls_head.yaml --stage train_cls --fold 1
jwzt train --config configs/train_finetune.yaml --stage finetune_all --fold 1

# Predict
jwzt pred --config configs/infer_busi.yaml --model checkpoints/best_auc.ckpt --data dataset/Dataset_BUSI_with_GT --output outputs/busi_predictions

# Evaluate
jwzt eval --config configs/eval_busi.yaml --pred outputs/busi_predictions --data dataset/Dataset_BUSI_with_GT

# Audit dataset
jwzt audit-data --data-root dataset --output outputs/dataset_audit_summary.json

# Debug training
jwzt train --config configs/train_debug.yaml --experiment-name debug_run

Clinical Workbench UI

The project now includes a clinical auxiliary diagnosis workbench for breast ultrasound cases:

• frontend source lives in web/
• packaged static UI lives in src/JwzTumor/server/ui/
• backend report generation lives in src/JwzTumor/server/report/
• report API endpoint is POST /api/report

The frontend supports:

• single-image and dual-image diagnosis modes
• patient metadata and structured ultrasound field entry
• asynchronous inference progress
• editable structured report rendering
• browser-local draft/history persistence
• JSON export and PDF export

Frontend Development

Install frontend dependencies:

cd web
npm install

Configure the API target with either .env or shell environment variables:

cp .env.example .env

.env example:

VITE_JWZT_API_BASE_URL=http://127.0.0.1:8000

Terminal temporary variable example:

cd web
VITE_JWZT_API_BASE_URL=https://your-api.example.com npm run dev -- --host 0.0.0.0 --port 5173

Start the standalone frontend dev server:

cd web
npm run dev -- --host 0.0.0.0 --port 5173

The frontend resolves the backend address in this order:

1. runtime config.js injected by the hosting server
2. VITE_JWZT_API_BASE_URL
3. fallback http://127.0.0.1:8000

Inference Server

Install server dependencies:

pip install -e ".[server]"

Start the inference API:

jwzt server \
  --model checkpoints/best_auc.ckpt \
  --config configs/infer_busi.yaml \
  --host 0.0.0.0 \
  --port 8000

The same values can also be stored in a server YAML file. Generate an annotated example with:

jwzt get -t server -o configs/server.yaml

Then start from that file:

jwzt server --config configs/server.yaml

Precedence is CLI options and their environment variables first, then YAML server: / report_llm: sections, then built-in defaults.

Useful CLI environment variables are also supported, so system variables and one-shot terminal variables work without editing code:

export JWZT_MODEL=checkpoints/best_auc.ckpt
export JWZT_CONFIG=configs/infer_busi.yaml
export JWZT_HOST=0.0.0.0
export JWZT_PORT=8000

Or:

JWZT_MODEL=checkpoints/best_auc.ckpt JWZT_PORT=8000 jwzt server

Server-related environment variables map directly to CLI options and YAML keys:

JWZT_MODEL                 -> server.model / --model
JWZT_HOST                  -> server.host / --host
JWZT_PORT                  -> server.port / --port
JWZT_DEVICE                -> server.device / --device
JWZT_TTA                   -> server.tta / --tta or --no-tta
JWZT_MAX_QUEUE             -> server.max_queue / --max-queue
JWZT_MAX_UPLOAD_MB         -> server.max_upload_mb / --max-upload-mb
JWZT_MAX_BATCH_SIZE        -> server.max_batch_size / --max-batch-size
JWZT_CORS_ORIGINS          -> server.cors_origins / --cors-origins
JWZT_LOG_DIR               -> server.log_dir / --log-dir
JWZT_WITH_UI               -> server.with_ui / --with-ui or --no-with-ui
JWZT_UI_DIR                -> server.ui_dir / --ui-dir
JWZT_UI_HOST               -> server.ui_host / --ui-host
JWZT_UI_PORT               -> server.ui_port / --ui-port
JWZT_UI_API_BASE_URL       -> server.ui_api_base_url / --ui-api-base-url
JWZT_NO_UI                 -> server.no_ui / --no-ui

UI Hosting Modes

Same-Port Hosting

Serve the packaged UI from the same FastAPI service and port:

jwzt server \
  --model checkpoints/best_auc.ckpt \
  --config configs/infer_busi.yaml \
  --with-ui \
  --host 0.0.0.0 \
  --port 8000

This serves:

• API: http://127.0.0.1:8000/api/...
• UI: http://127.0.0.1:8000/

Separate UI Port

Serve the API and UI on different ports:

jwzt server \
  --model checkpoints/best_auc.ckpt \
  --config configs/infer_busi.yaml \
  --with-ui \
  --host 0.0.0.0 \
  --port 8000 \
  --ui-host 0.0.0.0 \
  --ui-port 8080 \
  --ui-api-base-url http://127.0.0.1:8000

Equivalent environment variables:

export JWZT_UI_HOST=0.0.0.0
export JWZT_UI_PORT=8080
export JWZT_UI_API_BASE_URL=http://127.0.0.1:8000

If you already have an external built frontend directory, you can override the packaged UI:

jwzt server \
  --model checkpoints/best_auc.ckpt \
  --config configs/infer_busi.yaml \
  --with-ui \
  --ui-dir /absolute/path/to/web/dist

Runtime config.js

When the UI is served by jwzt server, the backend injects a runtime config.js file at /config.js:

window.__JWZT_CONFIG__ = { apiBaseUrl: "http://127.0.0.1:8000" };

This lets the same built frontend work in:

• local standalone development
• same-port packaged serving
• separate-port packaged serving
• reverse-proxy or public-domain deployments

Report API

Clinical report generation is exposed by:

POST /api/report

Supported report_mode values:

• rule: deterministic local rule template
• llm: editable sections generated by the configured LLM
• hybrid: rule template with LLM refinement and rule fallback on failure

The frontend uses /api/report first and falls back to a local rule composer if report generation fails.

OpenAI-Compatible LLM Configuration

/api/report can use any OpenAI-Compatible chat completions provider. Configure it with environment variables:

export JWZT_REPORT_LLM_BASE_URL=https://your-openai-compatible.example.com/v1
export JWZT_REPORT_LLM_API_KEY=sk-...
export JWZT_REPORT_LLM_MODEL=gpt-4.1-mini

Optional tuning variables:

export JWZT_REPORT_LLM_TIMEOUT=60
export JWZT_REPORT_LLM_MAX_RETRIES=2
export JWZT_REPORT_LLM_TEMPERATURE=0.2

The same provider settings can be placed in the server YAML:

report_llm:
  base_url: https://your-openai-compatible.example.com/v1
  api_key: sk-...
  model: gpt-4.1-mini
  timeout: 60
  max_retries: 2
  temperature: 0.2

Equivalent CLI flags are available:

jwzt server \
  --config configs/server.yaml \
  --report-llm-base-url https://your-openai-compatible.example.com/v1 \
  --report-llm-api-key sk-... \
  --report-llm-model gpt-4.1-mini

If these variables are absent, the report service stays in rule-only fallback mode for editable sections.

Rebuild Packaged UI

After changing the frontend, rebuild and copy the static bundle into the Python package:

./scripts/build_web_ui.sh

Training Strategy

Four-stage training:

1. pretrain_pre: Train LABDG-Pre only (coarse localization, structure maps)
2. pretrain_seg: Train DGBC-MTLNet segmentation (encoder + decoder)
3. train_cls: Train MPTC-Head only (freeze encoder + preprocessing)
4. finetune_all: End-to-end fine-tuning with all losses

Metrics

Classification: AUC, Accuracy, Sensitivity, Specificity, Precision, F1 Segmentation: Dice, IoU, HD95, Boundary-F1

Stargazers over time

License

Apache-2.0