Altar LegNet binding

altar-legnet is the lightweight control-plane binding for large-scale human LegNet MPRA activity variant scoring. It produces backend-neutral container plans and does not import PyTorch.

The binding scores hg38 SNVs in independently retryable Altar variant batches. Each variant contributes a 200 bp genomic context with the SNV at index 100; the runtime adds the published 5′ and 3′ 15 bp LentiMPRA adapters before the 230 bp model inference. The stable scalar effect is signed alt_activity - ref_activity.

Checkpoint bytes and the matching training configuration are independent, content-addressed resources. This supports the upstream K562, HepG2, and WTC11 models as well as compatible checkpoints without tying Altar to Zenodo, Hugging Face, Chorus, or another provider. The isolated executor is in runtimes/legnet. LegNetConfiguration uses the digest-pinned runtime tested with the binding by default; callers can override it with another immutable image reference.