AOP-toolkit (aoptk)
AOP-toolkit (aoptk) is a Python package for mining and analyzing toxicological and biomedical literature. Originally developed to support the construction of Adverse Outcome Pathways (AOPs), it provides general-purpose tools for retrieving, processing, and analyzing scientific publications.
The toolkit enables users to collect literature from databases such as PubMed Central and Europe PMC, extract information from full-text articles, analyze unstructured text and images using large language models, and normalize chemical names across publications to improve data consistency and interoperability.
How to use aoptk
Installation
You can install aoptk in multiple ways depending on your workflow.
Install from PyPI (with uv)
python -m pip install aoptk
Install from BioConda
conda install -c bioconda aoptk
Install from source (with uv)
git clone git@github.com:rdurnik/aoptk.git
cd aoptk
uv sync --frozen
uv pip install .
Dev Container (developer environment)
This repo includes a lightweight VS Code Dev Container in the .devcontainer/ folder. Rebuild it via VS Code: "Dev Containers: Rebuild Container".
To configure API access, copy .env.example to .env and fill in the required values before rebuilding the container.
Documentation
See our Read the Docs.
Contributing
If you want to contribute to the development of aoptk, have a look at the contribution guidelines.
Credits
This package was created with Copier and the NLeSC/python-template.
Funding
This software was developed with support from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 857560 (CETOCOEN Excellence) and from MEYS under grant SALVAGE (CZ.02.01.01/00/22_008/0004644). The content reflects only the author’s view, and the European Commission is not responsible for any use that may be made of the information it contains. Authors also thank the RECETOX Research Infrastructure (No LM2023069) financed by the Ministry of Education, Youth and Sports for supportive background.
1 maintainer
Metadata
1 maintainer
Release files for aoptk 0.5.0
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Source distribution (sdist)
| File | Size | Uploaded | Provenance | |
|---|---|---|---|---|
| aoptk-0.5.0.tar.gz | 2.4 MB | With provenance | Details |
Built distribution (wheel)
| File | Interpreter | ABI | Platform | Reset |
|---|---|---|---|---|
| aoptk-0.5.0-py3-none-any.whl | Python 3 | none | any | Details |
Total release size: 2.5 MB
Release files / aoptk-0.5.0.tar.gz
| Download URL | aoptk-0.5.0.tar.gz |
|---|---|
| Size | 2.4 MB |
| Tags | Source |
|
SHA-256 checksum How to use checksums |
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| Download URL | aoptk-0.5.0-py3-none-any.whl |
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| Size | 44.5 kB |
| Tags | Python 3 |
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SHA-256 checksum How to use checksums |
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Yes |
| Uploaded via |
twine/6.1.0 CPython/3.13.12
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Provenance
Provenance describes where a file came from. On PyPI, provenance is shared via attestations, which provide a verifiable record of the build or publishing details. View details, limitations and caveats.
PyPI Publish Attestation
PyPI verified that this artifact, at this checksum, originated from the publisher listed below.
Signed by GitHub Actions, verified by PyPI on Jun 11, 2026.
Transparency logSecurity for aoptk 0.5.0
Provenance
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Attestation for aoptk-0.5.0.tar.gz
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PyPI verified that this artifact, at this checksum, originated from the publisher listed below.
Signed by GitHub Actions, verified by PyPI on Jun 11, 2026.
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