Bone Microarchitecture
Lightweight microarchitecture measurements from binary masks and optional calibrated grayscale arrays.
This package intentionally has no Slicer dependency and no image I/O dependency. Callers are responsible for loading images, calibration, and putting masks on a common grid.
GPU Backends
Exact Hildebrand sphere fitting supports three diameter-accumulation backends:
cpu: NumPy/SciPy fallback.mps: native Apple Metal backend for macOS.opencl: OpenCL backend for Windows/Linux systems withpyopencland a working GPU OpenCL runtime.
Use thickness_backend="auto" to select Metal on macOS when available, OpenCL on Windows/Linux when available, and CPU otherwise.
Optional installs:
pip install "bone-microarchitecture[mps]"
pip install "bone-microarchitecture[opencl]"
pip install "bone-microarchitecture[gpu]"
Parameter Definitions
Tb.BMD: mean calibrated grayscale value inside the trabecular compartment.Tb.BV/TV: trabecular bone volume divided by trabecular total volume.Tb.Th: maximal-sphere local thickness of trabecular bone.Tb.Sp: maximal-sphere local thickness of non-bone space in the trabecular compartment.Tb.N: inverse ridge-to-ridge spacing estimate in the trabecular compartment.Tb.1/N.SD: standard deviation of ridge-to-ridge spacing.Tb.BV: trabecular bone volume.Tb.TV: trabecular compartment volume.Ct.BMD: mean calibrated grayscale value inside the cortical compartment.Ct.Th: maximal-sphere local thickness of cortical bone.Ct.Po: cortical pore volume divided by cortical total volume.Ct.Po.V: cortical pore volume.Ct.Po.Dm: maximal-sphere local diameter of cortical pore space.Ct.BV: cortical bone volume.Ct.TV: cortical compartment volume.
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