Change-O - Repertoire clonal assignment toolkit
Change-O is a collection of tools for processing the output of V(D)J alignment tools, assigning clonal clusters to immunoglobulin (Ig) sequences, and reconstructing germline sequences.
Dramatic improvements in high-throughput sequencing technologies now enable large-scale characterization of Ig repertoires, defined as the collection of trans-membrane antigen-receptor proteins located on the surface of B cells and T cells. Change-O is a suite of utilities to facilitate advanced analysis of Ig and TCR sequences following germline segment assignment. Change-O handles output from IMGT/HighV-QUEST and IgBLAST, and provides a wide variety of clustering methods for assigning clonal groups to Ig sequences. Record sorting, grouping, and various database manipulation operations are also included.
IMPORTANT! Active development of Change-O has moved to https://github.com/immcantation/changeo
6 maintainers
Release files for changeo 1.3.5
For a detailed explanation of source distributions (sdists) and built distributions (wheels), please see the package formats documentation.
Source distribution (sdist)
| File | Size | Uploaded | |
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| changeo-1.3.5.tar.gz | 165.3 kB | Details |
Release files / changeo-1.3.5.tar.gz
| Download URL | changeo-1.3.5.tar.gz |
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| Size | 165.3 kB |
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