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cobamp - pathway analysis methods for genome-scale metabolic models

Project description

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pyCoBAMP

pyCoBAMP (Constraint-Based Analysis of Metabolic Pathways) is a Python package containing pathway analysis methods for use with constraint-based metabolic models. The main purpose is to provide a framework that is both modular and flexible enough to be integrated in other packages (such as cobrapy, framed or cameo) that already implement generic data structures for metabolic models.

A (MI)LP solver is required for most of the methods. Current methods are implemented using CPLEX as a solver, although future versions will use a unifying solver platform, such as optlang.

Current methods include:
  • Elementary flux modes: K-Shortest algorithm

  • Minimal cut sets: MCSEnumerator approach

  • Elementary flux patterns: K-Shortest algorithm

Documentation

Instalation from PyPI (stable releases)

pip install cobamp

Instalation from github (latest development release)

pip install https://github.com/skapur/pyCoBAMP/archive/master.zip

Credits and License

Developed at the Centre of Biological Engineering, University of Minho

Released under the GNU Public License (version 3.0).

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