A bioinformatics tool for network analysis and visualization of gene sets.
Project description
Community Explorer (cx)
cx is a bioinformatics tool for network analysis and visualization of gene sets. It takes a list of genes, builds a protein-protein interaction network, identifies communities (functional modules) within the network, and performs functional enrichment analysis to uncover the biological significance of these communities.
Features
- Network Analysis: Constructs interaction networks from gene lists using the STRING database.
- Community Detection: Uses the Leiden algorithm to identify densely connected communities of genes.
- Enrichment Analysis: Performs functional enrichment analysis on gene communities using g:Profiler.
- Interactive Visualization: A web-based interface built with Streamlit allows for easy input and visualization of results.
Installation
To install the required dependencies, use pip with the pyproject.toml file:
pip install .
Usage
To run the web application, use the following command:
streamlit run app.py
This will start a local web server and open the application in your browser.
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