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configurable trainer for generative event models

Project description

Cotorra: a configurable trainer

PyPI Version DOI SWH

๐Ÿฆœ the wild parakeet of Chicago's south side

About

This repo provides a configurable trainer for generative event models on tokenized timelines. Cotorra is a Spanish term for a small-to-medium sized parrot, particularly the Monk parakeet. Monk parakeets were introduced to the south side of Chicago, where they have flourished. 1 It benefits from previous experience training foundation models on tokenized electronic health records. 2 3 4 5

Given a dataset of tokenized timelines, this package trains a model to predict the next token in a subject's timeline given their history up to that point, and then uses the trained model to extract representations and score outcomes of interest. It does all of this in a configurable way.

Installation

Install the latest release from PyPI:

pip install "cotorra" \
  --index-url https://download.pytorch.org/whl/cu128 \
  --extra-index-url https://pypi.org/simple

This installs the cotorra command. To work from source instead (e.g. to use generative scoring or for development):

git clone git@github.com:bbj-lab/cotorra.git
cd cotorra
python -m venv .venv
. .venv/bin/activate
pip install -e ".[gen]" \
  --index-url https://download.pytorch.org/whl/cu128 \
  --extra-index-url https://pypi.org/simple

Inputs

Suppose you have a dataset of tokenized timelines tokens_times.parquet as a parquet table with columns:

  • subject_id
  • tokens โ€” the integer token sequence for the subject's timeline.
  • times โ€” a parallel list of timestamps, one per token, indicating when each event occurred.

The table will look something like this:

โ”Œโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”ฌโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”ฌโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”
โ”‚ subject_id         โ”† tokens          โ”† times                           โ”‚
โ”‚ ---                โ”† ---             โ”† ---                             โ”‚
โ”‚ str                โ”† list[u32]       โ”† list[datetime[ฮผs]]              โ”‚
โ•žโ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•ชโ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•ชโ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•ก
โ”‚ 20002103           โ”† [20, 350, โ€ฆ 21] โ”† [2116-05-08 02:45:00, 2116-05-โ€ฆ โ”‚
โ”‚ 20008372           โ”† [20, 350, โ€ฆ 21] โ”† [2110-10-30 13:03:00, 2110-10-โ€ฆ โ”‚
โ”‚ โ€ฆ                  โ”† โ€ฆ               โ”† โ€ฆ                               โ”‚
โ”‚ 29994865           โ”† [20, 364, โ€ฆ 21] โ”† [2111-01-28 21:49:00, 2111-01-โ€ฆ โ”‚
โ””โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”ดโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”ดโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”˜

You also have a tokenizer.yaml, a plain yaml file that contains information about the configuration, learned vocabulary, and bins. This file is sufficient to reconstitute the tokenizer object. We only need this file to contain a lookup table:

lookup:
  UNK: 0
  ADMN//direct: 1
  ADMN//ed: 2
  ADMN//elective: 3
  AGE//age_Q0: 4
  ...

Finally, we need subject_splits.parquet which is a table listing out all subject_id's and their corresponding split assignment (with splits: train, tuning, and held_out). This table may include additional demographic information provided as pass-through-columns to cocoa.

โ”Œโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”ฌโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”
โ”‚ subject_id โ”† split    โ”‚
โ”‚ ---        โ”† ---      โ”‚
โ”‚ str        โ”† str      โ”‚
โ•žโ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•ชโ•โ•โ•โ•โ•โ•โ•โ•โ•โ•โ•ก
โ”‚ 21081215   โ”† train    โ”‚
โ”‚ 20302177   โ”† train    โ”‚
โ”‚ โ€ฆ          โ”† โ€ฆ        โ”‚
โ”‚ 28150003   โ”† held_out โ”‚
โ”‚ 22151813   โ”† held_out โ”‚
โ””โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”ดโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”˜

For extraction and scoring workflows, we also need split-specific inference tables in the same processed_data_home directory:

  • train_for_inference.parquet
  • tuning_for_inference.parquet
  • held_out_for_inference.parquet

These tables are expected to include at least:

  • tokens_past (the model context used for extraction/scoring)
  • s_elapsed_past (if using time_based_rope)
  • token-specific label columns such as <TOKEN>_past and <TOKEN>_future used by generative and representation-based scoring.

The cocoa winnow command provides these.

[!TIP] For getting your data to this point, check out our configurable collator / tokenizer: โ˜•๏ธ cocoa

Each command below is driven by a YAML config. The package ships a default for each command under src/cotorra/config/, which you can override by passing a config file via the appropriate CLI flag.

(1) Training

The trainer consumes the tokenized timelines and fits a causal language model to predict the next token in each subject's timeline. It:

  1. Builds a next-token-prediction dataset from tokens_times.parquet and the subject splits.
  2. Initializes a HuggingFace causal LM from a preset (or a custom architecture config).
  3. Optionally applies custom losses that upweight quantile-boundary tokens or tokens of clinical interest.
  4. Optionally uses time-aware rotary position embeddings so that position ids reflect elapsed time rather than token index.
  5. Trains the model โ€” optionally with differential privacy (cotorra train-private) or hyperparameter tuning (cotorra tune) โ€” and saves it.

Training is driven by a YAML config (the package ships a default; see ./src/cotorra/config/training.yaml) that specifies:

  • model:

    • model_name: Name or path of the HuggingFace model (e.g., meta-llama/Llama-3.2-1B).
    • model_args: Model architecture parameters passed directly to HuggingFace's AutoConfig.

    Note: The bundled config defines reusable model presets under model_presets.

  • max_seq_len: Maximum sequence length for model input.

  • n_epochs: Number of epochs (handled in the dataloader, not the trainer).

  • run_name: Name for the current run (referenced by wandb and training_args).

  • tokens_of_interest: List of special tokens to upweight during training (referenced by loss config). Supports patterns specified with fnmatch.

  • wandb:

    • project: Weights & Biases project name for experiment tracking.
    • run_name: Name for the current run.
  • custom_loss: Boolean flag to enable custom loss functions (default: false).

  • quantile_token_loss (optional): Upweights loss on quantile boundary tokens.

    • qt_weight: Weight multiplier for quantile tokens.
  • label_weighted_loss (optional): Upweights loss on specific tokens of clinical interest.

    • tokens_of_interest: List of token labels to upweight. Supports patterns specified with fnmatch.
    • toi_weight: Weight multiplier applied to those tokens.
  • time_based_rope (optional): Enables time-aware rotary position embeddings.

    • sec_per_pos_id: Number of seconds represented by one position id increment.
  • training_args: Arguments passed to HuggingFace's TrainingArguments.

  • tuning_args: Arguments passed to HuggingFace's hyperparameter_search when cotorra tune is called.

Model presets

We offer the following presets:

designator base model # params w/ ~1340-token vocab
llama_32 meta-llama/Llama-3.2-1B ~76.9M
llama_32_mid meta-llama/Llama-3.2-1B ~8.2M
qwen_3 Qwen/Qwen3-1.7B-Base ~74.1M
qwen_3_mid Qwen/Qwen3-1.7B-Base ~8.4M
gemma_3 google/gemma-3-1b-pt ~75.7M
gemma_3_mid google/gemma-3-1b-pt ~7.8M

Use the model key to select one of these presets and then override any individual model_args entries as needed.

[!TIP] Training supports the --resume-from-checkpoint (-r) flag. When set, cotorra train will attempt to resume from the latest HuggingFace checkpoint saved under --output-home. If no checkpoint is found (or resumption fails), it automatically falls back to training from scratch โ€” so the flag is safe to pass unconditionally in scripts. Use save_steps in training_args in the training.yaml file to control the frequency of checkpointing.

Differential privacy

We wrap opacus to support training with differential privacy (see cotorra train-private). The following relevant parameters can be modified in the configuration:

privacy_parameters:
    noise_multiplier: !!float 1.0
    max_grad_norm: !!float 1.0

Outputs

  • mdl-<run_name>/ โ€” the trained model, saved under --output-home in HuggingFace format (via save_pretrained), ready to be passed as --model-home to extract and the scoring commands.
  • mdl-<run_name>-training.yaml โ€” the resolved training configuration used for the run.

(2) Extraction

The extractor loads a trained model and computes hidden-state representations of each subject's context, suitable for representation-based scoring or downstream tasks. It:

  1. Loads the trained model from --model-home and the split-specific inference tables.
  2. Runs the model over each subject's tokens_past context.
  3. Extracts the hidden-state representation at the final position by default, or at all time steps when --all-times is set.
  4. Writes one feature table per split (optionally sharded).

Extraction is driven by a YAML config (the package ships a default; see ./src/cotorra/config/extraction.yaml) that specifies:

  • max_seq_len: Maximum sequence length.
  • time_based_rope (optional): Enables time-aware position ids during extraction (must match the setting used at training time).
    • sec_per_pos_id: Number of seconds represented by one position id increment.
  • extract:
    • max_len: Maximum input length (tokens) during extraction.
    • batch_size: Batch size for inference.
    • shard_size (optional): Number of samples per output parquet shard. Omit to write a single file per split.

Outputs

  • features-<split>-<model_name>.parquet โ€” extracted representations for each split (train, tuning, held_out). With --all-times, files are named features-all-<split>-<model_name>.parquet; when shard_size is set, each split is written across -<index>-of-<count> shards. These files are the input to cotorra rep-based-score.

(3) Scoring

Scoring uses a trained model to produce outcome scores for the tokens of interest. Two complementary approaches are provided:

Generative scoring (cotorra generative-score) Monte Carlo samples future trajectories directly from the model. It:

  1. Loads the trained model and held-out inference data.
  2. Samples future trajectories for each target token.
  3. Computes MC, SCOPE, and REACH scores per target token.

Note this depends on the quick-sco-re package.

Representation-based scoring (cotorra rep-based-score) fits a lightweight estimator on extracted features (run cotorra extract first). It:

  1. Loads the extracted features and label columns.
  2. Fits the chosen estimator on the training split.
  3. Predicts outcome probabilities for the held-out split.

Both are driven by a YAML config (the package ships a default; see ./src/cotorra/config/scoring.yaml) that specifies:

  • run_name: Name for the current run, used to label output files.
  • tokens_of_interest: List of token-based outcomes of interest. Supports patterns specified with fnmatch. (Referenced by target tokens.)
  • score:
    • max_len: Maximum input length (tokens) during scoring.
    • n_samp: Number of Monte Carlo samples per input per trajectory type.
    • target_tokens: Token-based outcomes of interest to score. Supports patterns specified with fnmatch.
    • end_tokens: Tokens that naturally terminate a generated sequence (e.g. EOS).
    • suppressed_tokens: Tokens to suppress via logit bias during generation (e.g. PAD).
    • trunc_id: Token id forced after the time horizon is exceeded.
    • max_time: Maximum time horizon in minutes.
    • batch_size: Batch size for inference.

Outputs

  • scores-generative-<model_name>.parquet โ€” held-out scores from generative-score, with a <TOKEN>_mc_score, <TOKEN>_scope_score, and <TOKEN>_reach_score column for each target token.
  • scores-rep-based-<model_name>.parquet โ€” held-out scores from rep-based-score, with a <TOKEN>_rep_score column for each target token.

Usage

We provide a CLI:

 Usage: cotorra [OPTIONS] COMMAND [ARGS]...

 Configurable training for generative event models (vXX.X.X)

โ•ญโ”€ Options โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฎ
โ”‚ --install-completion            Install completion for the current shell.   โ”‚
โ”‚ --show-completion               Show completion for the current shell, to   โ”‚
โ”‚                                 copy it or customize the installation.      โ”‚
โ”‚ --help                -h        Show this message and exit.                 โ”‚
โ•ฐโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฏ
โ•ญโ”€ Commands โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฎ
โ”‚ train             Train a model on tokenized data. For tokenization,        โ”‚
โ”‚                   consult the cocoa package.                                โ”‚
โ”‚ train-private     Train a model with differential privacy on tokenized      โ”‚
โ”‚                   data.                                                     โ”‚
โ”‚ tune              Run hyperparameter tuning while training a model.         โ”‚
โ”‚ extract           Extract representations from a trained model.             โ”‚
โ”‚ generative-score  Generate SCORE/REACH metrics from a trained model and     โ”‚
โ”‚                   save them to parquet.                                     โ”‚
โ”‚ rep-based-score   Generate rep-based scores for the token-based outcomes of โ”‚
โ”‚                   interest.                                                 โ”‚
โ”‚                   Note: this requires that features have already been       โ”‚
โ”‚                   extracted and saved                                       โ”‚
โ•ฐโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฏ

with commands:

  • cotorra train

    Usage: cotorra train [OPTIONS]
    
    Train a model on tokenized data. For tokenization, consult the cocoa package.
    
    โ•ญโ”€ Options โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฎ
    โ”‚    --training-config         -t      PATH  Training configuration file      โ”‚
    โ”‚                                            (overrides default)              โ”‚
    โ”‚ *  --processed-data-home     -p      TEXT  Processed data directory         โ”‚
    โ”‚                                            (overrides config)               โ”‚
    โ”‚                                            [required]                       โ”‚
    โ”‚ *  --output-home             -o      TEXT  Output directory for trained     โ”‚
    โ”‚                                            models                           โ”‚
    โ”‚                                            [required]                       โ”‚
    โ”‚    --resume-from-checkpoint  -r            Try to resume training from the  โ”‚
    โ”‚                                            latest checkpoint in             โ”‚
    โ”‚                                            --output-home.                   โ”‚
    โ”‚    --verbose                 -v            Verbose logging                  โ”‚
    โ”‚    --help                    -h            Show this message and exit.      โ”‚
    โ•ฐโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฏ
    
  • cotorra tune

    Usage: cotorra tune [OPTIONS]
    
    Run hyperparameter tuning while training a model.
    
    โ•ญโ”€ Options โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฎ
    โ”‚    --training-config      -t      PATH  Training configuration file         โ”‚
    โ”‚                                         (overrides default)                 โ”‚
    โ”‚ *  --processed-data-home  -p      TEXT  Processed data directory (overrides โ”‚
    โ”‚                                         config)                             โ”‚
    โ”‚                                         [required]                          โ”‚
    โ”‚ *  --output-home          -o      TEXT  Output directory for trained models โ”‚
    โ”‚                                         [required]                          โ”‚
    โ”‚    --verbose              -v            Verbose logging         โ”‚
    โ”‚    --help                 -h            Show this message and exit.         โ”‚
    โ•ฐโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฏ
    
  • cotorra train-private

    Usage: cotorra train-private [OPTIONS]
    
    Train a model with differential privacy on tokenized data.
    
    โ•ญโ”€ Options โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฎ
    โ”‚    --training-config      -t      PATH   Training configuration file        โ”‚
    โ”‚                                          (overrides default)                โ”‚
    โ”‚ *  --processed-data-home  -p      TEXT   Processed data directory           โ”‚
    โ”‚                                          (overrides config)                 โ”‚
    โ”‚                                          [required]                         โ”‚
    โ”‚ *  --output-home          -o      TEXT   Output directory for trained       โ”‚
    โ”‚                                          models                             โ”‚
    โ”‚                                          [required]                         โ”‚
    โ”‚    --noise-multiplier     -n      FLOAT  Noise multiplier (overrides        โ”‚
    โ”‚                                          configuration)                     โ”‚
    โ”‚    --max-grad-norm        -m      FLOAT  Max grad norm (overrides           โ”‚
    โ”‚                                          configuration)                     โ”‚
    โ”‚    --verbose              -v             Verbose logging                    โ”‚
    โ”‚    --help                 -h             Show this message and exit.        โ”‚
    โ•ฐโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฏ
    
  • cotorra extract

    Usage: cotorra extract [OPTIONS]
    
    Extract representations from a trained model.
    
    โ•ญโ”€ Options โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฎ
    โ”‚    --extraction-config    -e      PATH  Extraction configuration file       โ”‚
    โ”‚                                         (overrides default)                 โ”‚
    โ”‚ *  --processed-data-home  -p      TEXT  Processed data directory [required] โ”‚
    โ”‚ *  --model-home           -m      TEXT  Directory of the trained model to   โ”‚
    โ”‚                                         extract from                        โ”‚
    โ”‚                                         [required]                          โ”‚
    โ”‚    --output-home          -o      TEXT  Output directory for extracted      โ”‚
    โ”‚                                         features, defaults to               โ”‚
    โ”‚                                         processed-data-home                 โ”‚
    โ”‚    --all-times            -a            Extract features for all time steps โ”‚
    โ”‚                                         (instead of just the final one)?    โ”‚
    โ”‚    --help                 -h            Show this message and exit.         โ”‚
    โ•ฐโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฏ
    
  • cotorra generative-score

    Usage: cotorra generative-score [OPTIONS]
    
    Generate SCORE/REACH metrics from a trained model and save them to parquet.
    
    โ•ญโ”€ Options โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฎ
    โ”‚    --scoring-config       -s      PATH  Scoring configuration file          โ”‚
    โ”‚                                         (overrides default)                 โ”‚
    โ”‚ *  --processed-data-home  -p      TEXT  Processed data directory [required] โ”‚
    โ”‚ *  --model-home           -m      TEXT  Directory of the trained model to   โ”‚
    โ”‚                                         score with                          โ”‚
    โ”‚                                         [required]                          โ”‚
    โ”‚    --output-home          -o      TEXT  Output directory for scores,        โ”‚
    โ”‚                                         defaults to processed-data-home     โ”‚
    โ”‚    --verbose              -v            Verbose logging         โ”‚
    โ”‚    --help                 -h            Show this message and exit.         โ”‚
    โ•ฐโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฏ
    
  • cotorra rep-based-score (note: you need to run extract first)

    Usage: cotorra rep-based-score [OPTIONS]
    
    Generate rep-based scores for the token-based outcomes of interest. Note:
    this requires that features have already been extracted and saved
    
    โ•ญโ”€ Options โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฎ
    โ”‚    --scoring-config      -s      PATH                 Scoring configuration โ”‚
    โ”‚                                                       file (overrides       โ”‚
    โ”‚                                                       default)              โ”‚
    โ”‚ *  --processed-data-hoโ€ฆ  -p      TEXT                 Processed data        โ”‚
    โ”‚                                                       directory             โ”‚
    โ”‚                                                       [required]            โ”‚
    โ”‚ *  --model-home          -m      TEXT                 Directory of the      โ”‚
    โ”‚                                                       trained model to      โ”‚
    โ”‚                                                       score with            โ”‚
    โ”‚                                                       [required]            โ”‚
    โ”‚    --output-home         -o      TEXT                 Output directory for  โ”‚
    โ”‚                                                       scores, defaults to   โ”‚
    โ”‚                                                       processed-data-home   โ”‚
    โ”‚                                                       [default: None]       โ”‚
    โ”‚    --estimator           -e      [k-NN|lightGBM|logi  Estimator to use for  โ”‚
    โ”‚                                  stic|logistic-z|log  rep-based scoring     โ”‚
    โ”‚                                  istic-CV|logistic-C  [default: lightGBM]   โ”‚
    โ”‚                                  V-z|XGBoost]                               โ”‚
    โ”‚    --verbose             -v                           Verbose logging       โ”‚
    โ”‚    --help                -h                           Show this message and โ”‚
    โ”‚                                                       exit.                 โ”‚
    โ•ฐโ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ”€โ•ฏ
    
  1. L. Gersony, "The Quiet Victory of Chicagoโ€™s Monk Parakeets," The Chicago Maroon, 23 January 2022, https://chicagomaroon.com/28830/grey-city/quiet-protest-chicagos-monk-parakeets/ โ†ฉ

  2. M. Burkhart, B. Ramadan, Z. Liao, K. Chhikara, J. Rojas, W. Parker, & B. Beaulieu-Jones, Foundation models for electronic health records: representation dynamics and transferability, arXiv:2504.10422 โ†ฉ

  3. M. Burkhart, B. Ramadan, L. Solo, W. Parker, & B. Beaulieu-Jones, Quantifying surprise in clinical care: Detecting highly informative events in electronic health records with foundation models, Pacific Symposium on Biocomputing 31 (2026), 173โ€“188 โ†ฉ

  4. L. Solo, M. McDermott, W. Parker, B. Ramadan, M. Burkhart, & B. Beaulieu-Jones, Efficient generative prediction for EHR foundation models: the SCOPE and REACH estimators, arXiv:2602.03730 โ†ฉ

  5. I. Lee, L. Solo, M. Burkhart, B. Ramadan, W. Parker, & B. Beaulieu-Jones, Representation before training: a fixed-budget benchmark for generative medical event models, arXiv:2604.16775 โ†ฉ

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