Biomarkers of Critical Oscillations
Project description
crosci: biomarkers of Critical Oscillations
Collection of biomarkers for estimating criticality of neuronal oscillations:
- detrended fluctuation analysis (DFA), as implemented in [1]
- fE/I, a non-invasive estimate of E/I ratio [2]
The spectral ranges for computation of DFA and fE/I have been optimized in [3]
To reference, please cite the following papers:
- Hardstone, Richard, et al. "Detrended fluctuation analysis: a scale-free view on neuronal oscillations." Frontiers in physiology 3 (2012): 450.
- Bruining, Hilgo, et al. "Measurement of excitation-inhibition ratio in autism spectrum disorder using critical brain dynamics." Scientific reports 10.1 (2020): 9195.
- Diachenko, Marina, et al. "Functional excitation-inhibition ratio indicates near-critical oscillations across frequencies." Imaging Neuroscience 2 (2024): 1-17.
Running
The demo script (demo.py) exemplifies how DFA and fEI are computed for randomly generated data. You can use it as a starting point for your own data.
Building
We use uv and setuptools to build this package. As we also use Cyhton to improve performance you will need to have clang installed on your system
To build go into the source directory and do
uv build
This will both build a SDist and a wheel of the package for your machine.
Note
Crosci is also dependent on openmp, with is missing on modern MacOS clang version Apple ships. For the build to be succesfull you will need to install libomp as shown below:
brew install libomp
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