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Automated pelvimetry and body composition analysis from CT segmentations

Project description

ctpelvimetry

Automated CT pelvimetry and body composition analysis from CT segmentations.

Description and Features

ctpelvimetry is a Python package for automated pelvimetric measurement and body composition analysis from CT images. It integrates with TotalSegmentator for segmentation and provides a complete DICOM-to-results pipeline.

Pelvimetry Measurements

Metric Description
ISD (mm) Inter-Spinous Distance
Inlet AP (mm) Promontory → Upper Symphysis
Outlet AP (mm) Apex → Lower Symphysis
Outlet Transverse (mm) Intertuberous diameter
Outlet Area (cm²) Ellipse approx: π/4 × AP × Transverse
Sacral Length (mm) Promontory → Apex
Sacral Depth (mm) Max anterior concavity

Body Composition Measurements

Metric Description
VAT (cm²) Visceral Adipose Tissue area
SAT (cm²) Subcutaneous Adipose Tissue area
V/S ratio VAT / SAT ratio
SMA (cm²) Skeletal Muscle Area

Measured at L3 vertebral level and ISD (mid-pelvis) level.

Key Features

  • Per-metric error isolation — failure in one metric does not affect the others
  • Quality gates — automatic detection of pelvic rotation, tilt, and sacrum offset
  • Batch processing — process hundreds of patients with progress tracking and failure summaries
  • QC figures — sagittal combined, extended 3-panel, and body composition overlays
  • Modular design — use the full pipeline or individual analysis functions

Package Structure

ctpelvimetry/
├── __init__.py          # Public API
├── config.py            # PelvicConfig, constants
├── io.py                # Mask loading, coordinate transforms
├── conversion.py        # DICOM → NIfTI (dcm2niix)
├── segmentation.py      # TotalSegmentator execution
├── landmarks.py         # Midline, symphysis, sacral landmarks
├── metrics.py           # ISD, ITD, sacral depth
├── body_composition.py  # VAT/SAT/SMA analysis
├── qc.py                # QC figure generation
├── pipeline.py          # run_combined_pelvimetry, run_full_pipeline
├── batch.py             # Batch orchestration
└── cli.py               # Unified CLI entry point

Installation

# Basic install (analyse existing segmentations)
pip install ctpelvimetry

# Full install (includes TotalSegmentator for segmentation)
pip install "ctpelvimetry[seg]"

Note: The full install pulls in TotalSegmentator and its PyTorch dependencies. If you only need to analyse pre-existing segmentations, the basic install is sufficient.

Dependencies

Package Minimum Version
numpy ≥ 1.24
nibabel ≥ 5.0
pandas ≥ 2.0
scipy ≥ 1.11
matplotlib ≥ 3.7
tqdm ≥ 4.60
TotalSegmentator ≥ 2.0 (optional, pip install ".[seg]")

Usage Examples

CLI — Pelvimetry (from existing segmentation)

ctpelvimetry pelv \
  --seg_folder /path/to/segmentations \
  --nifti_path /path/to/ct.nii.gz \
  --patient Patient_001 \
  --output_root ./output --qc

CLI — Full Pipeline (DICOM → NIfTI → Seg → Measurements)

ctpelvimetry pelv \
  --dicom_dir /path/to/Patient_001 \
  --output_root ./output \
  --patient Patient_001

CLI — Body Composition

ctpelvimetry body-comp \
  --patient Patient_001 \
  --seg_root ./batch_output \
  --nifti_root ./batch_output \
  --pelvimetry_csv ./batch_output/combined_pelvimetry_report.csv \
  --output body_comp.csv --qc

CLI — Batch Processing

# Pelvimetry batch
ctpelvimetry pelv \
  --dicom_root /path/to/DICOMs \
  --output_root ./output \
  --start 1 --end 250

# Body composition batch
ctpelvimetry body-comp \
  --seg_root ./batch_output \
  --nifti_root ./batch_output \
  --pelvimetry_csv ./report.csv \
  --output body_comp.csv \
  --start 1 --end 210 --qc_root ./qc

Python API

from ctpelvimetry import run_combined_pelvimetry, process_single_patient

# Pelvimetry
result = run_combined_pelvimetry(
    "Patient_001", "/path/to/seg", "/path/to/ct.nii.gz"
)

# Body composition
result = process_single_patient(
    "Patient_001", "/path/to/seg_root",
    "/path/to/ct.nii.gz", "/path/to/report.csv"
)

Contributing

Contributions are welcome! Please follow these steps:

  1. Fork the repository
  2. Create a feature branch (git checkout -b feature/your-feature)
  3. Commit your changes (git commit -m "Add your feature")
  4. Push to the branch (git push origin feature/your-feature)
  5. Open a Pull Request

Citation

If you use ctpelvimetry in your research, please cite:

Manuscript in preparation. Citation details will be updated upon publication.

License

This project is licensed under the Apache License 2.0.

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