DASMixer Core

Core library for proteomics data project management, calculations, and data import.

Features

• Project management — create, open, save .dasmix files (SQLite)
• Data import — MGF (spectra), PowerNovo2 / MaxQuant / PLGS (identifications), FASTA (proteins)
• Calculations — ion matching (b/y/a/c/x/z), de novo PPM correction (SeqFixer), coverage calculation
• Peptide-to-protein mapping (npysearch BLAST)
• LFQ quantification — emPAI, iBAQ, NSAF, Top3 (via semPAI)
• Reports — PCA, Volcano, UpSet, Coverage, Sample Summary (Plotly-based)
• Export — HTML, DOCX, XLSX, mzTab

Installation

pip install dasmixer-core

With optional extras:

pip install "dasmixer-core[plotly]"     # Plotly + Kaleido for charts and export
pip install "dasmixer-core[proteins]"   # npysearch for BLAST-like search
pip install "dasmixer-core[all]"        # Full installation

Usage

from dasmixer.api.project.project import Project

async with Project(path="study.dasmix", create_if_not_exists=True) as project:
    samples = await project.get_samples()
    ...

Documentation: https://github.com/protdb/dasmixer