a package for Decomposition of Profile Data
Project description
depro
a package for Decomposition profile data analysis to grasp the effects of small compounds.
Dependency
- python 3.6
- requirements: numpy, pandas, scipy, tqdm, enan
Setup
pip install depro
- for conda environment, please use skeleton
Usage
see samplecode.ipynb
Licence
This software is released under the MIT License.
Authors
MIZUNO Tadahaya
References
This package is inspired from the following brilliant databases and studies:
- Nat Genet. 2003 Jul;34(3):267-73.
- PNAS. October 25, 2005 102 (43) 15545-15550.
- BMC Bioinformatics. 2013;128(14).
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update. Nucleic Acids Research. 2016; gkw377 .
- Science. 2006 Sep 29;313(5795):1929-35.
- MsigDB
- EnrichR
- CMap
Also our results: - Development of Orthogonal Linear Separation Analysis (OLSA) to Decompose Drug Effects into Basic Components. Mizuno T, Kinoshita S, Ito T, Maedera S, Kusuhara H., Sci Rep. 2019 Feb 12;9(1):1824. doi: 10.1038/s41598-019-38528-4.
Bug Report
If you would like to report any bugs about this package, don't hesitate to create an issue on github here, or email me:
To Do
- prepare sample code
Project details
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