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a package for Decomposition of Profile Data

Project description


a package for Decomposition profile data analysis to grasp the effects of small compounds.


  • python 3.6
  • requirements: numpy, pandas, scipy, tqdm, enan


pip install depro

  • for conda environment, please use skeleton


see samplecode.ipynb


This software is released under the MIT License.


MIZUNO Tadahaya


This package is inspired from the following brilliant databases and studies:

  • Nat Genet. 2003 Jul;34(3):267-73.
  • PNAS. October 25, 2005 102 (43) 15545-15550.
  • BMC Bioinformatics. 2013;128(14).
  • Enrichr: a comprehensive gene set enrichment analysis web server 2016 update. Nucleic Acids Research. 2016; gkw377 .
  • Science. 2006 Sep 29;313(5795):1929-35.
  • MsigDB
  • EnrichR
  • CMap
    Also our results:
  • Development of Orthogonal Linear Separation Analysis (OLSA) to Decompose Drug Effects into Basic Components. Mizuno T, Kinoshita S, Ito T, Maedera S, Kusuhara H., Sci Rep. 2019 Feb 12;9(1):1824. doi: 10.1038/s41598-019-38528-4.

Bug Report

If you would like to report any bugs about this package, don't hesitate to create an issue on github here, or email me:

To Do

  • prepare sample code

Project details

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Files for depro, version 0.0.11
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