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Hybrid Epidemic Intelligence: A framework for solving the inverse problem in SIRD models using dynamic parameter estimation.

Project description

DynaSIR: Forecasting COVID-19 using time series and machine learning

Note: DynaSIR (formerly epydemics) is the canonical package name going forward.

Version 1.0.0 - Official dynasir release and publication-ready reporting tools

dynasir is a Python library for epidemiological modeling and forecasting. It provides tools for creating, fitting, and evaluating discrete SIRD/SIRDV models with time-dependent parameters. The library is designed to be flexible and extensible, allowing users to easily incorporate their own data and models.

📖 New Users? Start with the User Guide to understand when and how to use dynasir.

v0.11.1 Features: Publication-ready reporting tools with ModelReport class for Markdown, LaTeX, and high-DPI figure export. See Reporting Guide for complete workflow examples.

Features

  • Discrete SIRD Model: A discrete Susceptible-Infected-Recovered-Deceased (SIRD) model with time-dependent parameters.
  • SIRDV Vaccination Model (v0.7.0): Extended model including Vaccinated compartment (V) and vaccination rate (δ).
  • Time Series Forecasting: Use of VAR (Vector Autoregression) models to forecast epidemic rates with logit transformation.
  • Multi-Frequency Support (v0.9.0): Native processing of daily, business day, weekly, monthly, and annual data with automatic detection and handler-based validation (no artificial reindexing).
  • Temporal Aggregation (v0.9.0): Frequency-aware aggregation that skips resampling when source and target frequencies match.
  • Business Day Support (v0.9.0): Dedicated handler for trading-day calendars (252 days/year) with validated lags and recovery windows.
  • Data Container: A convenient class for loading, preprocessing, and storing epidemiological data.
  • Parallel Simulations: Multi-core support for faster Monte Carlo simulations (27 scenarios for SIRD, 81 for SIRDV).
  • Result Caching: File-based caching to avoid recomputing identical analyses.
  • Model Evaluation: Tools for evaluating model performance with MAE, MSE, RMSE, MAPE, SMAPE metrics.
  • Visualization: Professional plotting functions for results and forecasts.
  • Reporting Tools (v0.11.1): Publication-ready report generation with Markdown, LaTeX, and high-DPI figure exports. See ModelReport class and examples/notebooks/07_reporting_and_publication.ipynb.

✅ Native Multi-Frequency: v0.9.0 processes annual/monthly/weekly/business-day data without artificial daily reindexing. See User Guide for frequency guidance.

SIRDV Model (New in v0.7.0)

The SIRDV model extends the classical SIRD model by incorporating vaccination:

Compartments:

  • S: Susceptible
  • I: Infected (active cases)
  • R: Recovered
  • D: Deaths
  • V: Vaccinated (new)

Rates:

  • α: Infection rate
  • β: Recovery rate
  • γ: Mortality rate
  • δ: Vaccination rate (new)

Key Features:

  • Automatic detection from vaccination data
  • 81 simulation scenarios (3⁴ confidence levels)
  • Conservation law: N = S + I + R + D + V
  • Parallel execution recommended for performance

Quick Start: Reporting

Generate publication-ready reports with one API:

from dynasir import DataContainer, Model
from dynasir.analysis import ModelReport

# Fit model (see Tutorial for full workflow)
container = DataContainer(data, mode='incidence')
model = Model(container)
model.create_model()
model.fit_model(max_lag=3)
model.forecast(steps=10)
model.run_simulations()
model.generate_result()

# Generate comprehensive report
report = ModelReport(model.results, testing_data=test_data)
report.export_markdown("report.md", include_figure=True)
report.export_latex_table("table.tex", "summary")
fig = report.plot_forecast_panel(dpi=600, save_path="forecast.png")

See: Reporting Guide | Notebook Example | Script Example

Getting Started

To get started with dynasir, we recommend following the tutorial in TUTORIAL.md.

Installation

You can install dynasir from PyPI:

pip install dynasir

To install the latest development version, you can clone this repository and install it in editable mode:

git clone https://github.com/julihocc/dynasir.git
cd dynasir
pip install -e .

Documentation

User Documentation:

  • User Guide: Complete guide on when to use dynasir, data preparation, and frequency handling
  • Tutorial: Step-by-step guide for COVID-19 forecasting
  • CHANGELOG.md: Version history and detailed changes

Developer Documentation:

Release Documentation:

Further work

Recent additions in v0.10.0:

  • Fractional Recovery Lag: Annual frequency now uses 14/365 years (0.0384) instead of 0, fixing LinAlgError with incidence mode
  • Annual + Incidence Mode: Production-ready native support for annual surveillance data with incident cases
  • Enhanced Testing: 10 new tests for fractional lag validation (421/423 tests passing)

Recent additions in v0.9.0:

  • Native Multi-Frequency: Daily, business day, weekly, monthly, annual handlers; no artificial reindexing
  • Frequency-Aware Aggregation: Skip resampling when source and target frequencies match
  • Frequency-Aware Seasonality: Adaptive seasonal detection per frequency
  • Business Day Support: Trading-day defaults (252 days/year, 10-lag VAR, 10-day recovery)

Previous releases (v0.6.1-v0.7.0):

  • SIRDV Model Support: Automatic detection and modeling of vaccination data
  • Parallel Simulations: Multi-core execution for improved performance
  • Result Caching: Optional caching to avoid recomputation
  • Enhanced Testing: Comprehensive test coverage with slow test markers

Future directions (v1.0.0+):

  • Incidence-First Mode: Direct modeling of incident cases (not just cumulative)
  • Importation Modeling: Handle external case introductions for eliminated diseases
  • Probabilistic & Scenario Forecasting: Monte Carlo and intervention comparison workflows
  • More advanced time series models: SARIMAX, Prophet, or deep learning approaches
  • Support for other epidemiological models: Extend to SEIR, SEIRD, or metapopulation models
  • Improved visualization: Interactive dashboards and real-time updating plots

References

Allen u.a. 2008 Allen, L.J.S. ; Brauer, F. ; Driessche, P. van den ; Bauch, C.T. ; Wu, J. ; Castillo-Chavez, C. ; Earn, D. ; Feng, Z. ; Lewis, M.A. ; Li, J. u.a.: Mathematical Epidemiology. Springer Berlin Heidelberg, 2008 (Lecture Notes in Mathematics).– URL https://books. google.com/books?id=gcP5l1a22rQC.– ISBN 9783540789109

Andrade u.a. 2021 Andrade, Marinho G. ; Achcar, Jorge A. ; Conce icc˜ ao, Katiane S. ; Ravishanker, Nalini: Time Series Regression Models for COVID-19 Deaths. In: J. Data Sci 19 (2021), Nr. 2, S. 269–292

Hawas 2020 Hawas, Mohamed: Generated time-series prediction data of COVID-19s daily infections in Brazil by using recurrent neural networks. In: Data in brief 32 (2020), S. 106175

Maleki u.a. 2020 Maleki, Mohsen ; Mahmoudi, Mohammad R. ; Wraith, Darren ; Pho, Kim-Hung: Time series modelling to forecast the confirmed and recovered cases of COVID-19. In: Travel medicine and infectious disease 37 (2020), S. 101742

Martcheva 2015 Martcheva, M.: An Introduction to Mathematical Epi demiology. Springer US, 2015 (Texts in Applied Mathematics).– URL https: //books.google.com/books?id=tt7HCgAAQBAJ.– ISBN 9781489976123

Singh u.a. 2020 Singh, Vijander ; Poonia, Ramesh C. ; Kumar, Sandeep ; Dass, Pranav ; Agarwal, Pankaj ; Bhatnagar, Vaibhav ; Raja, Linesh: Prediction of COVID-19 coronavirus pandemic based on time series data using Support Vector Machine. In: Journal of Discrete Mathematical Sciences and Cryptography 23 (2020), Nr. 8, S. 1583–1597

Wacker und Schluter 2020 Wacker, Benjamin; Schluter, Jan: Time continuous and time-discrete SIR models revisited: theory and applications. In: Advances in Difference Equations 2020 (2020), Nr. 1, S. 1–44.– ISSN 1687-1847.– URL https://doi.org/10.1186/s13662-020-02907-9

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