epistabase 0.1.0

EpistaBase Python SDK and CLI for notebook and platform data access

EpistaBase Python SDK

epistabase is the governed Python client for the EpistaBase platform. It gives notebooks, scripts, and the epistabase CLI typed, authenticated access to the same projects, experiments, catalog, queries, sequences, and imaging you use in the browser — without ever handling raw storage credentials.

It is a thin client: it wraps the EpistaBase API and nothing more. Data engines, parsers, query planners, and statistics stay on the server or in your own environment.

Naming: you install the distribution epistabase, but the import package is currently biolake (import biolake as bl) and the environment variables are BIOLAKE_*. A full internal rename to epistabase is in progress.

Install

pip install epistabase

Optional extras pull in heavier dependencies only when you need them:

pip install "epistabase[image]"   # numpy/pillow for tiled image reads
pip install "epistabase[cli]"     # the `epistabase` command-line interface

The SDK requires Python 3.12.

Authenticate

The SDK authenticates with a scoped bearer token and an active workspace. There are two ways to get one.

Browser login (CLI)

epistabase auth login              # opens your browser, stores the token locally
epistabase auth status             # shows who you are and the active workspace

Credentials are written to ~/.epistabase/credentials.json. Access is governed entirely by your EpistaBase account — installing the SDK grants nothing on its own.

Token / environment

For headless use (CI, servers, notebook kernels), provide a Personal Access Token and workspace through the environment:

export BIOLAKE_API_URL="https://api.biolake.example"
export BIOLAKE_TOKEN="your-personal-access-token"   # or BIOLAKE_PAT
export BIOLAKE_WORKSPACE_ID="workspace-id"
export BIOLAKE_EXPERIMENT_ID="experiment-id"        # optional context
export BIOLAKE_NOTEBOOK_ID="notebook-id"            # optional context

The SDK never reads AWS, S3, or MinIO credentials. All data access flows through governed BioLake API/data-plane services.

Command-line data access

The same operations are available from the epistabase CLI, sharing the SDK's credentials and governance. Once you have authenticated (above), the verbs run against your active workspace:

epistabase ls --experiment EXP-12        # discover catalog assets   (--json to script)
epistabase get EXP-12/cells.fcs          # show an asset's metadata + lineage
epistabase pull EXP-12/cells.fcs         # download the data         (defaults to ./cells.fcs)
epistabase query "SELECT * FROM counts"  # run governed SQL          (--out result.parquet to save)

Every command takes an opaque asset id or a readable [experiment/]name path (ambiguous names report the candidates). get shows metadata; pull downloads the bytes, or materializes a table to .csv / .parquet.

Quickstart

import biolake as bl

# Query governed lakehouse tables
rows = bl.query("select * from current_table limit 10")

# Discover catalog assets
images = bl.assets(experiment="EXP-2026-0001", kind="IMAGE")
asset = bl.get(images[0].id)

# Promote a notebook output back into the experiment
result = bl.publish_figure(fig, name="Dose response", format="svg")
print(result.download_url)

The implicit session reads the environment above on first use. Pass an explicit Session when you need more than one context in the same process.

Publishing figures and tables

Notebook outputs can be promoted back into the current experiment. The SDK renders the local object, sends bytes to the API, and the API stores the artifact in governed storage:

result = bl.publish_figure(fig, name="Dose response", format="svg")
result.catalog_asset_id
result.download_url

table = bl.publish_table(df, name="Summary table")  # CSV by default

publish_figure() accepts raw bytes, matplotlib figures with savefig(), and plotly figures with to_image(). publish_table() accepts raw bytes, CSV text, or dataframe-like objects with to_csv() / to_parquet(). Published artifacts use BIOLAKE_EXPERIMENT_ID unless experiment_id= is given, and record the source notebook id plus the query log from prior bl.query() calls.

Catalog discovery

bl.assets(...) lists catalog assets visible to your token. Filters are server-side and governed by the same read authorization as the web app:

assets = bl.assets(experiment="EXP-2026-0001", kind="FLOW", tags=["sort-1"])
asset = bl.get(assets[0].id)

asset.kind              # "FLOW", "IMAGE", "TABLE", "VOLUME", ...
asset.format            # "fcs", "tiff", ...
asset.size_bytes
asset.experiment_number
asset.lineage

AssetRef and Asset are descriptors; they never expose standing storage credentials. Type-specific accessors such as biolake.image layer on top.

Image reads

pip install "epistabase[image]"

biolake.image resolves image assets through the catalog, mints short-lived WSI tile sessions, and reads only bounded regions or thumbnails through the tile service:

img = bl.assets(experiment="EXP-2026-0001", kind="IMAGE")[0]

info = bl.image.info(img)
region = bl.image.read_region(img, 0, 0, 2048, 2048, level=2, channels=["DAPI"])
overview = bl.image.thumbnail(img, max_px=1024)
rois = bl.image.annotations(img)            # read-only GeoJSON ROIs

Whole-blob reads

bl.open(asset_id) streams whole raw blobs (FCS, vendor exports, gel TIFFs, CSV/XLSX) via a short-lived presigned GET URL:

with bl.open("asset-id") as f:
    header = f.read(64)

with bl.open("asset-id", byte_range=(0, 1023)) as f:
    first_kb = f.read()

with bl.open("asset-id", download=True) as path:   # for libraries needing a path
    parse_vendor_file(path)

open() is whole-blob only; tiled/pyramidal images go through biolake.image.

Notebook kernels

Inside an EpistaBase notebook kernel the environment is injected for you (a short-lived scoped token plus a refresh URL), so import biolake as bl works with no setup. The same code runs locally once you set the environment above or run epistabase auth login.

Development

This package is developed inside the EpistaBase monorepo under sdk/ but is released independently. From a checkout:

cd sdk
uv run --extra dev pytest -q
uv run --extra dev ruff check .
uv run --extra dev mypy src --strict

See AGENTS.md for the thin-client scope rules and docs/adr/ADR-012 for the packaging and distribution decision.

License

Proprietary. © EpistaBase. Use of the SDK is governed by your EpistaBase agreement.