escapepod

Fast Python reader/writer for Oxford Nanopore POD5 files, backed by a pure Rust engine (the same engine as the escpod CLI). It mirrors the API of Oxford Nanopore's official pod5 package closely enough to be a mostly drop-in replacement, while reading and writing considerably faster.

Alpha quality and under active development. APIs and output formats may change without notice. Verify results against the official ONT pod5 tools before relying on it for anything important.

Install

uv pip install escapepod

Wheels are published for CPython 3.9+ (abi3) on Linux (x86_64/aarch64, manylinux + musllinux) and macOS (x86_64/arm64).

Usage

import escapepod

with escapepod.Reader("experiment.pod5") as reader:
    print(f"{reader.read_count} reads")
    for read in reader:
        signal = reader.get_signal(read)          # raw ADC (int16)
        print(read.read_id, read.num_samples, signal.mean())

See the documentation for the full API.

License

MIT

Project links

Data verified by PyPI on Aug 15, 2026
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Key dates

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  • Released:
Newer release available (0.26.0)

1 maintainer

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Avatar for jayhesselberth from gravatar.com jayhesselberth

Credits

Author: Jay Hesselberth

GitHub Statistics

Data verified by PyPI on Aug 15, 2026
The GitHub source repository was provided by the project maintainers and verified by PyPI at the time of upload. Stars, forks, and open issues/PRs are derived from that repository and have not been independently verified.

License expression

MIT
View SPDX License List

Requires

Python >=3.9

Tags

nanopore pod5 sequencing bioinformatics signal

Classifiers

Report project as malware

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