Model Context Protocol (MCP) server for Fiji/ImageJ: macros, discovery, screenshots, and workflows via PyImageJ
Project description
Fiji MCP Server
Talk to Fiji / ImageJ in plain English from Cursor, Claude, Gemini, Windsurf, and more.
Open images, run any ImageJ plugin, count cells, measure features, take screenshots to verify — without writing a single line of macro code yourself.
See it in action
"Open the image, apply a Gaussian blur, show me before and after."
| Before | After |
|---|---|
"Threshold the bright spots, outline each object, report area and circularity."
| Input | Outlined objects |
|---|---|
| # | Area | Circularity |
|---|---|---|
| 1 | 1052 | 0.89 |
| 2 | 2840 | 0.72 |
| 3 | 641 | 0.91 |
| 4 | 1902 | 0.68 |
"Skeletonize the mask and summarize branches per tree."
| Mask | Skeleton |
|---|---|
| Tree | Branches | Junctions |
|---|---|---|
| 1 | 14 | 6 |
| 2 | 9 | 7 |
Get started in 3 steps
1 — Install
pip install fiji-mcp-server
You need Python 3.10+, Fiji installed on your machine, and Java (required by PyImageJ). See quickstart if anything needs clarification.
2 — Connect to your AI app
Replace /Applications/Fiji with your actual Fiji folder (the one containing jars/ and plugins/).
| App | One command |
|---|---|
| Claude Desktop | fiji-mcp-install install claude-desktop --fiji-path /Applications/Fiji |
| Cursor | fiji-mcp-install install cursor --fiji-path /Applications/Fiji |
| Claude Code | fiji-mcp-install install claude-code --fiji-path /Applications/Fiji |
| Gemini CLI | fiji-mcp-install install gemini --fiji-path /Applications/Fiji |
| Windsurf | fiji-mcp-install install windsurf --fiji-path /Applications/Fiji |
Then restart the app.
3 — Verify it works
In chat, type:
Run the Fiji MCP health_check tool
You should get back the Fiji version and mode. First startup takes 30–90 seconds while the JVM loads — that's normal.
What to ask
Once connected, just describe what you want:
"Open ./images/cells.tif and tell me the dimensions."
"Apply a Gaussian blur with sigma 4 and show me the result."
"Count the bright objects and give me their areas."
"Search for ImageJ commands related to 'threshold'."
"Open the image, subtract background, threshold, count particles — show me a screenshot after each step."
No macro knowledge needed. The assistant finds the right Fiji plugin, runs it, and can show you a screenshot to verify.
Available tools (19 total)
| Category | Tools |
|---|---|
| Run & I/O | health_check run_macro run_batch_macros open_image save_image |
| Screenshots | screenshot_fiji — full screen, active image, or results table |
| Discover plugins | list_all_commands search_commands describe_plugin list_extensions |
| Image info | list_open_images get_image_info |
| Workflows | run_workflow — chain steps with screenshot verification |
| Results | parse_macro_output compare_screenshots list_macro_templates get_macro_template |
| Session | get_session_trace clear_session_trace |
Documentation
| Quick start | Install, configure, verify — step by step |
| All tools | What every tool does and when to use it |
| Configuration | Environment variables and troubleshooting |
| Architecture | How the pieces fit together |
Author: Suraj Sahu · UC Merced Physics · ssahu2@ucmerced.edu
Related: cellpose_mcp · PyImageJ · FastMCP
License: BSD-3-Clause
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