frame-alignment-checks 0.0.2

Library for determining whether a RNA splicing predictor is using frame alignment information

Frame alignment checks

Set of tools for checking whether splicing prediction models are using frame alignment information. Does so on a set of "long canonical internal coding exons", that is, exons that

• appear in the SAM validation set (first half of the SpliceAI test set) of canonical exons in certain chromosomes
• have exactly one ensembl annotation whose transcript is the same as the canonical transcript
• start and end in a coding region
• length at least 100nt

this set is built in to the package and does not need to be provided by the user.