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Model Context Protocol server for Galaxy bioinformatics platform

Project description

Galaxy MCP Server - Python Implementation

This is the Python implementation of the Galaxy MCP server, providing a Model Context Protocol server for interacting with Galaxy instances.

Features

  • Complete Galaxy API integration through BioBlend
  • Interactive Workflow Composer (IWC) integration
  • FastMCP2 server with remote deployment support
  • Type-annotated Python codebase

Requirements

  • Python 3.10+
  • FastMCP 2.3.0+

Installation

From PyPI (Recommended)

# Install from PyPI
pip install galaxy-mcp

# Or using uv (recommended)
uvx galaxy-mcp

From Source

# Clone the repository
git clone https://github.com/galaxyproject/galaxy-mcp.git
cd galaxy-mcp/mcp-server-galaxy-py

# Install with uv (recommended)
uv sync --all-extras

Configuration

The server requires Galaxy credentials to connect to an instance. You can provide these via environment variables:

export GALAXY_URL=<galaxy_url>
export GALAXY_API_KEY=<galaxy_api_key>

Alternatively, create a .env file in the project root with these variables.

Usage

Quick Start with uvx

The fastest way to run the Galaxy MCP server is using uvx:

# Run the server directly without installation
uvx galaxy-mcp

# Run with FastMCP2 dev tools
uvx --from galaxy-mcp fastmcp dev src/galaxy_mcp/server.py

# Run as remote server
uvx --from galaxy-mcp fastmcp run src/galaxy_mcp/server.py --transport sse --port 8000

As a standalone MCP server

# Install and run the MCP server
pip install galaxy-mcp
galaxy-mcp

# The server will wait for MCP protocol messages on stdin

With MCP clients

# Use with FastMCP2 CLI tools
fastmcp dev src/galaxy_mcp/server.py
fastmcp run src/galaxy_mcp/server.py

# Use with other MCP-compatible clients
your-mcp-client galaxy-mcp

See USAGE_EXAMPLES.md for detailed usage patterns and common examples.

Available MCP Tools

The Python implementation provides the following MCP tools:

  • connect: Establish connection to a Galaxy instance
  • search_tools_by_name: Find Galaxy tools by name
  • get_tool_details: Retrieve detailed tool information
  • run_tool: Execute a Galaxy tool with parameters
  • get_tool_panel: Retrieve the Galaxy tool panel structure
  • get_tool_run_examples: Retrieve XML-defined test lessons that show how to run a tool
  • get_user: Get current user information
  • get_histories: List available Galaxy histories
  • list_history_ids: Get simplified list of history IDs and names
  • get_history_details: Get detailed information about a specific history
  • upload_file: Upload local files to Galaxy
  • upload_file_from_url: Upload files from URLs to Galaxy
  • list_workflows: List available workflows in Galaxy instance
  • get_workflow_details: Get detailed information about a specific workflow
  • invoke_workflow: Execute/run a workflow with specified inputs
  • cancel_workflow_invocation: Cancel a running workflow invocation
  • get_invocations: View workflow executions
  • get_iwc_workflows: Access Interactive Workflow Composer workflows
  • search_iwc_workflows: Search IWC workflows by keywords
  • import_workflow_from_iwc: Import an IWC workflow to Galaxy

Testing

The project includes a comprehensive test suite using pytest with mock-based testing.

Running Tests

# Install test dependencies
uv pip install -r requirements-test.txt

# Run all tests
uv run pytest

# Run with coverage report
uv run pytest --cov=main --cov-report=html

# Run specific test file
uv run pytest tests/test_history_operations.py

# Run tests with verbose output
uv run pytest -v

Test Structure

Tests are organized by functionality:

  • test_connection.py - Galaxy connection and authentication
  • test_history_operations.py - History-related operations
  • test_dataset_operations.py - Dataset upload/download
  • test_tool_operations.py - Tool search and execution
  • test_workflow_operations.py - Workflow import and invocation
  • test_integration.py - End-to-end scenarios

See tests/README.md for more details on the testing strategy.

Development

Code Style Guidelines

  • Use Python 3.10+ features
  • Employ type hints where appropriate
  • Follow PEP 8 style guidelines
  • Use ruff for code formatting and linting
  • All code should pass type checking with mypy

Development Setup

# Install development dependencies
make install-dev

# Set up pre-commit hooks (required for contributing)
uv run pre-commit install

Pre-commit hooks will automatically format your code and run linting checks when you commit. All contributors should install these hooks to maintain consistent code quality.

Development Commands

We use a Makefile for consistent development commands:

# Show all available commands
make help

# Install dependencies
make install       # Install all dependencies

# Code quality
make lint          # Format code and run all checks

# Testing
make test          # Run tests with coverage

# Building
make clean         # Clean build artifacts
make build         # Build distribution packages

# Running
make run           # Run the MCP server
make dev           # Run FastMCP2 dev server

Using uv directly

All commands can also be run directly with uv:

# Install dependencies
uv sync --all-extras

# Format and lint code
uv run pre-commit run --all-files

# Run tests with coverage
uv run pytest --cov=galaxy_mcp --cov-report=html

# Update dependencies
uv lock --upgrade

Cross-version Testing

Test across multiple Python versions using tox:

# Test on all supported Python versions
tox

# Test on specific version
tox -e py312

# Run only linting
tox -e lint

# Run type checking
tox -e type

Pre-commit Hooks

The project uses pre-commit hooks for automatic code quality checks:

# Install pre-commit hooks (one-time setup)
uv run pre-commit install

# Run pre-commit manually on all files
uv run pre-commit run --all-files

# Skip pre-commit for a single commit (not recommended)
git commit --no-verify

Pre-commit runs automatically on git commit and includes:

  • Code formatting with ruff
  • Linting with ruff
  • Trailing whitespace removal
  • File cleanup (EOF, YAML/JSON/TOML validation)
  • Large file detection
  • Merge conflict detection

License

MIT

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