gwyddionpy

Read any raw scanning probe microscopy (SPM) file that Gwyddion supports — around 170 vendor formats — into Python as NumPy arrays plus metadata dictionaries. Pure Python: the parsing is done by the gwyconvert helper binary, run as a subprocess.

import gwyddionpy

data = gwyddionpy.load("scan.spm")
data.channels["Height"].data      # numpy array, physical values
data.metadata                     # vendor metadata
data.to_json("scan.json")         # metadata only, no pixel data
data.to_hdf5("scan.h5")           # optional: pip install 'gwyddionpy[hdf5]'

gwyconvert is installed separately, most simply with pip install "gwyddionpy[converter]". See the repository README for the other options and for the licensing split (this package is Apache-2.0; the converter is GPL-2.0-or-later).