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Educational Clustal Omega implementation for Bioinformatics Multiple Sequence Alignment

Project description

ilaydaMSA

Bu proje, Biyoinformatik dersi için Çoklu Dizi Hizalaması (Multiple Sequence Alignment - MSA) amacıyla sıfırdan geliştirilmiş, eğitim amaçlı bir Clustal Omega algoritması kütüphanesidir.

İçerdiği algoritmalar ve adımlar:

  • K-mer tabanlı uzaklık matrisi hesaplama
  • UPGMA yöntemi ile Kılavuz Ağaç (Guide Tree) oluşturma
  • Profile-HMM tabanlı Kademeli Hizalama (Progressive Alignment)
  • Consensus Sequence oluşturma
  • Hizalama istatistiklerini raporlama

Kurulum

Bu kütüphaneyi bilgisayarınıza indirmek için aşağıdaki komutu terminalinizde çalıştırabilirsiniz:

pip install ilaydaMSA

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