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Project description

Incenp.Bioutils -’s utilities for computational biology

Incenp.Bioutils is a set of command line utilities and helper Python modules to deal with some computational biology tasks.



SeqTool is intended as a “Swiss Army knife” to perform various operations on biological sequence files.

Among other things, it provides wrappers for the blast and dotter alignment tools; the main interest of those wrappers is that they can be used with sequences in any format supported by Biopython’s SeqIO module, whereas the original tools only read files in the FASTA format.


SeqVault is a command-line interface to BioSQL databases.

SeqVault is intended to be used with a slightly modified version of the BioSQL database schema (provided in the biosql directory), where every biodatabase is associated with a 3-letters prefix. That prefix is then used to automatically assign accession numbers (of the form PRE_xxxxxx where PRE is the prefix) when importing sequences into the database. However SeqVault can also be used with pristine BioSQL databases.

Quickstart (example with PostgreSQL)

Create a new PostgreSQL user account and a new database::

# createuser <username>
# createdb -O owner <username> <dbname>

Initialize the newly created database by running the provided biosql/biosqldb-pg.sql script::

$ psql -h localhost -U <username> <dbname> < biosql/biosqldb-pg.sql

Next, create a plaintext file in $XDG_CONFIG_HOME/bioutils/databases.ini and fill it as follows::

host: localhost
user: <username>
password: <PostgreSQL user password>
database: <dbname>

SeqVault is now ready to be used.


CC3d-Runner is a small wrapper around the command-line interface of CompuCell3D, to run headless simulations.

Helper modules

The main helper module is the module, which provides an implementation of the Uniform Sequence Address format .

A Uniform Sequence Address or USA is a way to refer to a biological sequence and to fetch that sequence from its source.

The following example shows how to read a sequence specified by a USA::

from import usa

records = usa.read_usa('')

The returned records object is an array of Bio.SeqRecord.SeqRecord objects.


The following Python packages are necessary:

ReportLab is required to run the plasmm subcommand of the seqtool utility.

The seqvault utility requires a SQL adapter for the database server you plan to use it with, such as psycopg2 for PostgreSQL.


Incenp.Bioutils is distributed under the terms of the GNU General Public License, version 3 or higher. The full license is included in the COPYING file of the source distribution.

Homepage and repository

The project is located at The source code is available in a Git repository at

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