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iscc (in silico cancer center) is a multi-modal tumor evolution data simulator. It grows one selection-driven, spatially-structured tumor, optionally treats it, samples it, and generates single-cell and bulk DNA, RNA, and spatial data, down to sequencing reads. Because every run knows the true clones, mutations, copy numbers, cell states, spatial niches, and lineages, iscc provides a realistic ground truth for benchmarking computational tumor evolution methods.

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0.3.0 This release

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0.2.0

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0.1.2

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