iris-vector-graph 1.1.4

Knowledge graph and vector search platform on InterSystems IRIS for financial services and biomedical applications

IRIS Vector Graph

A knowledge graph system built on InterSystems IRIS that combines graph traversal, vector similarity search, and full-text search in a single database.

NEW: Interactive Demo Server showcasing fraud detection + biomedical capabilities

Proven at Scale Across Industries:

• Financial Services: Real-time fraud detection (130M+ transactions), bitemporal audit trails, <10ms queries
• Biomedical Research: Protein interaction networks (100K+ proteins), drug discovery, <50ms multi-hop queries

Same IRIS platform. Different domains. Powerful results.

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Table of Contents

• Quick Start
  • Option A: Fraud Detection (Financial Services)
  • Option B: Biomedical Graph (Life Sciences)
• Use Cases by Industry
• Architecture
• Key Features
• Performance
• Documentation

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Quick Start

Two Deployment Modes:

1. External (DEFAULT - simpler): Python app connects to IRIS via iris.connect()
2. Embedded (ADVANCED - optional): Python app runs INSIDE IRIS container

Option A: Fraud Detection (Financial Services)

External Mode (Default - Simpler)

# 1. Start IRIS database
docker-compose up -d

# 2. Install Python dependencies
pip install iris-vector-graph        # Core features
pip install iris-vector-graph[ml]    # + Machine learning (fraud scoring models)

# 3. Load fraud schema
docker exec -i iris /usr/irissys/bin/irissession IRIS -U USER < sql/fraud/schema.sql

# 4. Start fraud API (external Python)
PYTHONPATH=src python -m iris_fraud_server

# Test fraud scoring API
curl -X POST http://localhost:8000/fraud/score \
  -H 'Content-Type: application/json' \
  -d '{"mode":"MLP","payer":"acct:test","device":"dev:laptop","amount":1000.0}'

Embedded Mode (Advanced - Optional)

# Run FastAPI INSIDE IRIS container (licensed IRIS required)
docker-compose -f docker-compose.fraud-embedded.yml up -d

# Test fraud scoring API (~2 min startup)
curl -X POST http://localhost:8100/fraud/score \
  -H 'Content-Type: application/json' \
  -d '{"mode":"MLP","payer":"acct:test","device":"dev:laptop","amount":1000.0}'

What you get:

• FastAPI fraud scoring (external :8000 or embedded :8100)
• Bitemporal data (track when transactions happened vs. when you learned about them)
• Complete audit trails (regulatory compliance: SOX, MiFID II)
• Direct IRIS queries (no middleware)

Learn more: examples/bitemporal/README.md - Fraud scenarios, chargeback defense, model tracking

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Option B: Biomedical Graph (Life Sciences)

External Mode (Default - Simpler)

# 1. Start IRIS database
docker-compose up -d

# 2. Install dependencies
curl -LsSf https://astral.sh/uv/install.sh | sh
uv sync && source .venv/bin/activate

# 3. Load STRING protein database (10K proteins, ~1 minute)
python scripts/performance/string_db_scale_test.py --max-proteins 10000

# 4. Start interactive demo server (external Python)
PYTHONPATH=src python -m iris_demo_server.app

# 5. Open browser
open http://localhost:8200/bio

Embedded Mode (Advanced - Optional)

# Run demo server INSIDE IRIS container (licensed IRIS required)
# Coming soon - currently only external mode supported for biomedical demo

What you get:

• Interactive protein search with vector similarity (EGFR, TP53, etc.)
• D3.js graph visualization with click-to-expand nodes showing interaction networks
• Pathway analysis between proteins using BFS graph traversal
• Real STRING DB data (10K proteins, 37K interactions)
• <100ms queries powered by direct IRIS integration (no API middleware)
• 20/20 contract tests passing - production-ready biomedical demo

Learn more:

• docs/biomedical-demo-setup.md - Complete setup guide with scaling options
• biomedical/README.md - Architecture and development patterns

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Use Cases by Industry

Financial Services (IDFS)

Use Case	Features	Performance
Real-Time Fraud Detection	Graph-based scoring, MLP models, device fingerprinting	<10ms scoring, 130M+ transactions
Bitemporal Audit Trails	Valid time vs. system time, chargeback defense, compliance	<10ms time-travel queries
Late Arrival Detection	Settlement delay analysis, backdated transaction flagging	Pattern detection across 130M events
Regulatory Compliance	SOX, GDPR, MiFID II, Basel III reporting	Complete audit trail preservation

Files:

• examples/bitemporal/ - Fraud scenarios, audit queries, Python API
• sql/bitemporal/ - Schema (2 tables, 3 views, 8 indexes)
• src/iris_fraud_server/ - FastAPI fraud scoring server
• docker-compose.fraud-embedded.yml - Licensed IRIS + embedded Python

Quick Links:

• Bitemporal Fraud Detection README
• Fraud API Documentation

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Biomedical Research

Use Case	Features	Performance
Protein Interaction Networks	STRING DB integration, pathway analysis, vector similarity	<50ms multi-hop queries (100K+ proteins)
Drug Discovery	Compound similarity, target identification, graph analytics	<10ms vector search (HNSW)
Literature Mining	Hybrid search (embeddings + BM25), entity extraction	RRF fusion, sub-second queries
Pathway Analysis	Multi-hop traversal, PageRank, connected components	NetworkX integration, embedded Python

Files:

• biomedical/ - Protein queries, pathway examples
• sql/schema.sql - Graph schema (nodes, edges, properties, embeddings)
• iris_vector_graph/ - Core Python graph engine
• docker-compose.acorn.yml - ACORN-1 with HNSW optimization

Quick Links:

• Biomedical Examples
• STRING DB Integration

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Graph Algorithms (TSP Examples)

Two standalone implementations of the Traveling Salesman Problem demonstrating graph algorithms on IRIS:

Option A: Python + NetworkX (Biomedical)

Find optimal pathways through protein interaction networks:

# Test with 10 cancer-related proteins
python scripts/algorithms/tsp_demo.py --proteins 10 --compare-methods

Algorithms: Greedy (1ms), Christofides (15ms), 2-opt (8ms) Use case: Optimize order to study protein interactions in cancer pathways

Option B: ObjectScript (Healthcare Interoperability)

Optimize caregiver routes for home healthcare:

# Load sample data (8 patients, 26 travel edges)
docker exec -i iris /usr/irissys/bin/irissession IRIS -U USER < sql/caregiver_routing_demo.sql

# Run optimization demo (IRIS Terminal)
Do ^TestCaregiverRouter

Performance: <2ms for 8-patient routes Integration: Direct Business Process method calls Impact: 53% travel time reduction (75min → 35min)

What you get:

• Python approach: NetworkX integration, multiple algorithms, FastAPI endpoint example
• ObjectScript approach: Zero dependencies, Interoperability production integration, bitemporal audit
• Comprehensive docs: Neo4j comparison, performance benchmarks, real-world use cases

Files:

• scripts/algorithms/tsp_demo.py - Python demo (works with STRING protein data)
• iris/src/Graph/CaregiverRouter.cls - ObjectScript TSP optimizer
• iris/src/Graph/ScheduleOptimizationProcess.cls - Business Process integration
• sql/caregiver_routing_demo.sql - Sample healthcare data

Learn more:

• docs/algorithms/TSP_ANALYSIS.md - Deep dive and Neo4j comparison
• docs/algorithms/TSP_IMPLEMENTATION_SUMMARY.md - Overview and benchmarks
• docs/examples/CAREGIVER_ROUTING_DEMO.md - Step-by-step tutorial

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Architecture

Deployment Options:

• External (Default): Python app connects to IRIS via iris.connect() - simpler setup, easier debugging
• Embedded (Advanced): Python app runs inside IRIS container - maximum performance, requires licensed IRIS

External Deployment (DEFAULT)        Embedded Deployment (OPTIONAL)
┌────────────────────────┐          ┌──────────────────────────────┐
│ FastAPI Server         │          │ IRIS Container               │
│ (external Python)      │          │ ┌──────────────────────────┐ │
│                        │          │ │ FastAPI Server           │ │
│  iris.connect()   ─────┼──────────┤►│ (/usr/irissys/bin/       │ │
│  to localhost:1972     │          │ │  irispython)             │ │
└────────────────────────┘          │ └──────────────────────────┘ │
                                    │ ┌──────────────────────────┐ │
                                    │ │ IRIS Database Engine     │ │
                                    │ │ (Bitemporal/Graph/Vector)│ │
                                    │ └──────────────────────────┘ │
                                    └──────────────────────────────┘

         Same Platform: InterSystems IRIS
         Same Features: Vector Search, Graph Traversal, Bitemporal Audit
         Different Domains: Finance vs. Life Sciences

Core Components:

• IRIS Globals: Append-only storage (perfect for audit trails + graph data)
• Embedded Python: Run ML models and graph algorithms in-database
• SQL Procedures: kg_KNN_VEC (vector search), kg_RRF_FUSE (hybrid search)
• HNSW Indexing: 100x faster vector similarity (requires IRIS 2025.3+ or ACORN-1)

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Key Features

Cross-Domain Capabilities

Feature	Financial Services Use	Biomedical Use
Embedded Python	Fraud ML models in-database	Graph analytics (PageRank, etc.)
Personalized PageRank	Entity importance scoring	Document ranking, pathway analysis
Temporal Queries	Bitemporal audit ("what did we know when?")	Time-series biomarker analysis
Graph Traversal	Fraud ring detection (multi-hop)	Protein interaction pathways
Vector Search	Transaction similarity	Protein/compound similarity
Partial Indexes	WHERE system_to IS NULL (10x faster)	WHERE label = 'protein'

IRIS-Native Optimizations

• Globals Storage: Append-only (no UPDATE contention)
• Partial Indexes: Filter at index level (WHERE system_to IS NULL)
• Temporal Views: Pre-filter current versions
• Foreign Key Constraints: Referential integrity across graph
• HNSW Vector Index: 100x faster than flat search (ACORN-1)
• PPR Functional Index: ObjectScript $LISTBUILD + $LISTNEXT for 8.9x faster PageRank at scale (10K nodes: 184ms vs 1,631ms Python)

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Performance

Financial Services (Fraud Detection)

Metric	Community IRIS	Licensed IRIS
Transactions	30M	130M
Database Size	5.3GB	22.1GB
Fraud Scoring	<10ms	<10ms
Bitemporal Queries	<10ms (indexed)	<10ms (indexed)
Time-Travel Queries	<50ms	<50ms
Late Arrival Detection	Pattern search across 30M	Pattern search across 130M

Biomedical (Protein Networks)

Metric	Pure Python	ObjectScript Native
Vector Search	5800ms (flat) → 1.7ms (HNSW)	Same (HNSW index)
Multi-hop Queries	<50ms	<50ms
Hybrid Search (RRF)	<100ms	<20ms
Personalized PageRank (1K)	14.5ms	14.3ms
Personalized PageRank (10K)	1,631ms	184ms (8.9x faster) ✨
Graph Analytics	NetworkX integration	Zero-copy Global access

Tested At Scale:

• ✅ 130M fraud transactions (licensed IRIS)
• ✅ 100K+ protein interactions (STRING DB)
• ✅ 768-dimensional embeddings (biomedical models)

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Usage Examples

Personalized PageRank (PPR)

Compute entity importance scores for knowledge graph ranking:

from iris_vector_graph import IRISGraphEngine
import iris

# Connect to IRIS
conn = iris.connect("localhost", 1972, "USER", "_SYSTEM", "SYS")
engine = IRISGraphEngine(conn)

# Compute PPR scores from seed entity
scores = engine.kg_PERSONALIZED_PAGERANK(
    seed_entities=["PROTEIN:TP53"],  # Seed with cancer protein
    damping_factor=0.85,              # Standard PageRank parameter
    top_k=20                          # Return top 20 scored entities
)

# Results: {'PROTEIN:TP53': 0.152, 'PROTEIN:MDM2': 0.087, ...}

# Rank documents by PPR scores
docs = engine.kg_PPR_RANK_DOCUMENTS(
    seed_entities=["PROTEIN:TP53"],
    top_k=10
)

# Results: [{document_id, score, top_entities, entity_count}, ...]

Performance: <25ms for 1K entities, ~200ms for 10K entities (Python implementation)

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Documentation

Getting Started

• Fraud Detection Quick Start
• Biomedical Graph Setup
• Installation Guide

Architecture & Design

• System Architecture
• IRIS-Native Features
• Performance Benchmarks

API Reference

• REST API
• Python SDK
• SQL Procedures

Examples

• Bitemporal Fraud Detection
• Protein Interaction Networks
• Migration to NodePK

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Repository Structure

sql/
  schema.sql              # Core graph schema
  bitemporal/             # Fraud detection schema
  fraud/                  # Transaction tables

examples/
  bitemporal/             # Financial services (fraud, audit)

biomedical/               # Life sciences (proteins, pathways)

iris_vector_graph/   # Python graph engine

src/iris_fraud_server/    # FastAPI fraud API

scripts/
  fraud/                  # 130M loader, benchmarks
  migrations/             # NodePK migration

docker/
  Dockerfile.fraud-embedded      # Licensed IRIS + fraud API
  start-fraud-server.sh          # Embedded Python startup

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License

MIT License - See LICENSE

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Contributing

We welcome contributions! This repo demonstrates IRIS versatility across:

• Financial Services: Fraud detection, bitemporal data, regulatory compliance
• Biomedical Research: Protein networks, drug discovery, literature mining

Feel free to add examples from other domains or improve existing implementations.

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Production-Ready: Proven with 130M+ financial transactions and 100K+ biomedical interactions on InterSystems IRIS.