A research workbench for running and inspecting multi-agent research topics.
Project description
isomer-labs
Isomer Labs is a research workbench for running multi-agent research topics from a project directory. It gives operators a CLI, packaged system skills, topic workspaces, durable records, and a local web GUI for inspecting how ideas, experiments, and artifacts evolve.
Install
Install the CLI as a uv tool:
uv tool install isomer-labs
isomer-cli --help
For development from a checkout, use Pixi:
pixi install
pixi run isomer-cli --help
Start a Project
mkdir my-isomer-project
cd my-isomer-project
isomer-cli project init
isomer-cli project topics create my-topic --statement "Investigate the concrete research question." --set-default
isomer-cli --print-json project validate
Start the local GUI over the project directory:
isomer-cli project web serve --root .
Then open the printed local URL and choose the Research Topic to inspect.
Topic Workspace Explained
An Isomer Project can contain many Research Topics. Each topic gets its own Topic Workspace, usually under isomer-content/topic-ws/<topic-id>/, and that workspace is the topic's storage and execution boundary.
The Topic Workspace owns the topic Pixi environment. Dependencies for research code, profiling scripts, renderers, and validation tools should be added to the Topic Workspace pixi.toml, not silently installed into the Project root or the user's global Python. This keeps one topic's runtime requirements from leaking into another topic.
The Topic Workspace also owns the research storage layout:
intent/stores the topic overview, environment gate, actor definitions, and derived setup gates.records/stores durable research records, artifacts, evidence items, decisions, view manifests, and the SQLite index used by the GUI.runtime/stores Workspace Runtime state, adapter payloads, launch material, and resumable execution state.repos/topic-main/is the topic-owned development repository for code-bearing work.repos/extern/stores canonical external repositories such as upstream source checkouts.actors/andagents/store actor or agent workspaces, usually as worktrees ofrepos/topic-main.
The Project Manifest records where each Topic Workspace lives, while topic-workspace.toml inside the workspace binds semantic labels such as topic.repos.main, topic.records, and topic.runtime to concrete paths. Agents and skills should resolve those labels instead of guessing paths.
Install System Skills
Install packaged Isomer skills with isomer-cli system-skills install. The entrypoint skill is included in the core group and is the best starting point for operators because it routes known tasks to the right Isomer skill or CLI command.
isomer-cli system-skills install --target codex
Supported targets are claude-code, codex, kimi-code, generic, and all. codex installs to $CODEX_HOME/skills or ~/.codex/skills; generic installs to .agents/skills; claude-code installs to .claude/skills; kimi-code installs to .kimi-code/skills.
Install the DeepSci extension when a project needs the research pipeline skills:
isomer-cli system-skills install --target codex --extension deepsci
Inspect or remove Isomer-owned projections with:
isomer-cli system-skills status --target codex
isomer-cli system-skills uninstall --target codex
Getting Started With CLI Agent
After the CLI and skills are installed, drive Isomer from your coding agent with short skill calls and follow-up prompts.
Create the Research Topic
The user starts with a concrete research goal and wants the agent to turn it into an Isomer Research Topic with durable intent files.
User Action:
$isomer-op-topic-creator create topic: Investigate the concrete research question and define the expected evidence.
AI:
Created the Research Topic, wrote the topic overview and environment gate, and stopped for review.
Prepare the Topic Workspace
The user wants the agent to set up only what the topic needs, verify the environment, and report blockers before research begins.
User Action:
$isomer-op-topic-creator run-to setup-topic-env
AI:
Prepared the Topic Workspace, verified dependencies, and reported readiness or blockers.
Run a Bounded Research Pass
The user wants one controlled research pass, not unattended automation, and expects the agent to return artifacts plus a next route.
User Action:
$isomer-deepsci-pipeline empirical-pass
AI:
Ran a bounded research pass, recorded artifacts, and reported the next route.
Tighten the Evidence
The user sees that a claim needs stronger evidence and asks the agent to separate what is already supported from what must be measured next.
User Prompt:
Tighten the evidence: compare the model against real measurements, explain mismatches, and revise the next experiment.
AI:
Separated supported claims from missing evidence and proposed a follow-up pass.
Write the Paper
The user wants the accepted records turned into a readable paper artifact, with review blockers surfaced rather than hidden.
User Action:
$isomer-deepsci-pipeline paper-pass
AI:
Drafted or revised the paper from accepted records, built the artifact, and reported review blockers.
For concrete prompt and response patterns, start with Research Workflow Tutorials.
Documentation
Status
The project is early but usable for local research-project setup, topic workspace management, record indexing, and GUI inspection. See Assumptions and Roadmap for current boundaries.
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