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Package for converting between genome build coordinates

Project description


python liftover utility

Converts point coordinates between genome assemblies. Inspired by pyliftover, this offers a few advantages:

  • ~5X faster, and lower memory requirements, as loading the chain file and converting coordinates is implemented in c++.
  • dictionary style conversion, as in access converted coordinates via converter[chrom][pos]


Install via pip: pip install liftover


from liftover import get_lifter

converter = get_lifter('hg19', 'hg38')
chrom = '1'
pos = 103786442

converter.query(chrom, pos)

# alternatively create a converter directly from a chainfile
from liftover import ChainFile
converter = ChainFile('/home/user/hg18ToHg38.over.chain.gz', 'hg18', 'hg38')

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Files for liftover, version 1.1.3
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