Locat identifies marker genes enriched within a compact subset of cells and depleted elsewhere
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Locat
This package is an implementation of Locat. Locat identifies marker genes with concentrated expression domains while excluding broadly expressed background genes across diverse biological contexts.
The documentation is available at https://klugerlab.github.io/Locat. Additional code and supporting information for the Locat paper is available at https://github.com/Klugerlab/Locat-paper.
Installation
The main version of the package can be installed as
pip install locat
The package is based on jax (see installation instructions).
To enable jax with GPU or TPU, install jax with cuda support.
For example, if your system has cuda12, install locat as:
pip install locat jax[cuda12]
The development version of the package can be installed as
pip install git+https://github.com/Klugerlab/Locat.git
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