mAbLab
mAbLab is a Python library for analyzing monoclonal antibody (mAb) characteristics with domain granularity.
Features
- Analyze VL, VC, VH, CH1, CH2, CH3, Fab, LC, HC, Fc, andHinge domains of antibodies.
- Calculate protein properties such as molecular weight, isoelectric point, and extinction coefficients.
- Annotate CDR regions and infer germline genes.
- number sequences with Kabat, Martin, IMGT numbering schemes
Installation
Install the library using pip:
pip install mAbLab
Usage
import mAbLab
# Example sequences
hc_sequence = "EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHW..."
lc_sequence = "DIQMTQSPSSLSASVGDRVTITCRASQGIRNYLAW..."
# Create a Mab object
mab = mAbLab.Mab(hc1_aa_sequence=hc_sequence, lc1_aa_sequence=lc_sequence)
# Access Fab properties
print(mab.fab1.properties.charge_at_ph(6))
License
This project is licensed under the MIT License. See the LICENSE file for details.
1 maintainer
Metadata
1 maintainer
Release files for mAbLab 1.1.0
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Source distribution (sdist)
| File | Size | Uploaded | Provenance | Actions |
|---|---|---|---|---|
| mablab-1.1.0.tar.gz | 28.7 kB | Without provenance | Details for mablab-1.1.0.tar.gz |
Built distribution (wheel)
| File | Interpreter | ABI | Platform | Actions Reset |
|---|---|---|---|---|
| mablab-1.1.0-py3-none-any.whl | Python 3 | none | any | Details for mablab-1.1.0-py3-none-any.whl |
Total release size: 57.3 kB
Release files / mablab-1.1.0.tar.gz
| Download URL | mablab-1.1.0.tar.gz |
|---|---|
| Size | 28.7 kB |
| Tags | Source |
|
SHA-256 checksum How to use checksums |
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BLAKE2b-256 checksum How to use checksums |
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No |
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twine/6.2.0 CPython/3.11.7
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Release files / mablab-1.1.0-py3-none-any.whl
| Download URL | mablab-1.1.0-py3-none-any.whl |
|---|---|
| Size | 28.7 kB |
| Tags | Python 3 |
|
SHA-256 checksum How to use checksums |
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BLAKE2b-256 checksum How to use checksums |
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Uploaded using Trusted Publishing? What is trusted publishing? |
No |
| Uploaded via |
twine/6.2.0 CPython/3.11.7
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Security for mAbLab 1.1.0
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