META Trial EDC (https://www.isrctn.com/ISRCTN76157257)

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META EDC

Metformin treatment in Africa - META

py 3.12+ / DJ 5.2 using the Clinic EDC framework

This codebase is used for two randomized clinical trials:

META PHASE II:

(final version 0.1.77)

Metformin Treatment for Diabetes Prevention in Africa: META Trial TASO, MRC/UVRI/LSHTM, NIMR – TZ and Liverpool School of Tropical Medicine (ISRCTN76157257) http://www.isrctn.com/ISRCTN76157257

META PHASE III:

A randomised placebo-controlled double-blind phase III trial to determine the effects of metformin versus placebo on the incidence of diabetes in HIV-infected persons with pre-diabetes in Tanzania.

Liverpool School of Tropical Medicine

EDCTP grant number: RIA2018CO-2513

Trial registration: ISCRTN 77382043

https://ico.org.uk/ESDWebPages/Entry/Z4763134

See also https://github.com/clinicedc/edc

Made with Django

Installation

As of version 1.1.10, we are building and deploying with uv.

Here we assume you have your DB setup and already have your .env file.

First-time install

Assuming you are logged into the account myaccount:

mkdir -p ~/.etc/meta && \
mkdir ~/edc && \
cd ~/edc && \
uv venv && \
uv pip install -U meta-edc==2.4.0 && \
wget https://raw.githubusercontent.com/meta-trial/meta-edc/2.4.0/manage.py && \
uv pip freeze | grep meta-edc

Copy your .env file to ~/.etc.

Place this at or near the end of your .bashrc:

# >>> EDC using uv >>>
export DJANGO_SETTINGS_MODULE=meta_edc.settings.uat
export META_PHASE=3
export DJANGO_BASE_DIR=/home/myaccount/edc
export DJANGO_ENV_DIR=/home/myaccount/.etc/
cd ~/edc
source .venv/bin/activate
export PATH="/home/myaccount/edc:$PATH"
# <<< EDC using uv <<<

Source .bashrc and run manage.py check.

source ~/.bashrc && \
cd ~/edc && \
python manage.py check

If all is OK, run migrate:

Explicitly specify the settings file when using migrate.

  • live: --settings=meta_edc.settings.live

  • uat: --settings=meta_edc.settings.uat

  • debug: --settings=meta_edc.settings.debug

cd ~/edc && \
python manage.py migrate --settings=meta_edc.settings.live

Update an existing install

From the above example:

cd ~/edc && \
uv venv --clear && \
uv pip install -U meta-edc==2.4.0 && \
wget -O manage.py https://raw.githubusercontent.com/meta-trial/meta-edc/1.1.10/manage.py && \
uv pip freeze | grep meta-edc && \
python manage.py check

If all is OK, run migrate

cd ~/edc && \
python manage.py migrate --settings=meta_edc.settings.live

Project details

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