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Metaseed

Metaseed

CI codecov PyPI Python 3.11+ License: MIT

Metaseed creates, edits, and validates scientific metadata against a standard, from a YAML specification of that standard.

Documentation · Introduction slides · Changelog

What it does

A metadata standard such as MIAPPE or ISA is written as a profile: a YAML file that names the entity types, their fields, the parent–child hierarchy, and the validation rules. From that file, Metaseed:

  • Generates Pydantic models for every entity type at runtime.
  • Validates a dataset with composable rules: required fields, patterns, ranges, uniqueness, referential integrity, and conditions.
  • Serializes datasets to JSON, YAML, and Excel, and back.
  • Exports to the formats repositories take: ISA-Tab, ENA XML, PRIDE submission.px with SDRF, DCAT, and SEEK's ISA RDF.
  • Pushes a dataset into a running FAIRDOM-SEEK instance, or to a shared metaseed-hub.

You work with it from a command line, a web interface, a Python API, or an MCP server for an AI agent. All four reach the same library functions, and a test fails when one of them falls behind the others.

Install

Metaseed requires Python 3.11 or later.

uv tool install metaseed

To include an integration, name its extra. For example, metaseed[seek,dcat] adds the FAIRDOM-SEEK and DCAT adapters; metaseed[hub] adds the hub client. The Plugins page in the web interface lists which extras are installed.

For development:

git clone https://github.com/sorenwacker/metaseed.git
cd metaseed
make setup

Profiles

The package ships these profiles. Counts refer to each profile's latest version.

Profile --profile Versions Entities Fields Domain
MIAPPE miappe 1.1, 1.2 14 163 Plant phenotyping
MIAPPE-HTP miappe-htp 1.0 28 137 High-throughput plant phenotyping
ISA isa 1.0 22 139 Life science investigations
Darwin Core darwin-core 1.0 10 189 Biodiversity
DiSSCo dissco 0.4 16 261 Digital specimens
ENA ena 1.0 11 109 Nucleotide archive submissions
MetaboLights metabolights 1.0 13 71 Metabolomics
PRIDE pride 1.0, 2.0 9 61 Proteomics
SEEK seek 1.0 24 229 The FAIRDOM-SEEK data model
SEEK-ready template seek-ready-template 1.0, 2.0, 3.0 6 33 Minimal ISA shape for a SEEK upload

Profiles you write yourself go under ~/.local/share/metaseed/specs/. The web interface's spec builder and the metaseed spec commands author them; the explorer compares them; metaseed merge combines them.

Integrations

An adapter is a route in or out of a dataset. A profile is a standard; an adapter is a service or file format. Each adapter is a pip extra of the same name.

Adapter Direction What it does
FAIRDOM-SEEK push, export Creates Sample Types and Extended Metadata on a SEEK instance and pushes a dataset as ISA content; exports SEEK-importable ISA RDF (guide)
Metaseed Hub push, pull Pushes datasets and profiles to a metaseed-hub and pulls them back, never overwriting without being asked (guide)
DCAT export Exports a dataset's catalogue record as DCAT, in JSON-LD and Turtle
ENA import, export Imports the metadata of a European Nucleotide Archive accession; exports ENA XML
PRIDE import, export Imports a PRIDE Archive project; exports submission.px and SDRF
MetaboLights import Imports a MetaboLights study document
BrAPI import Imports a BrAPI v2 server's studies into the MIAPPE profile

Use it

Command line

The CLI is grouped by what you act on. Every group prints its own help, for example metaseed dataset --help.

metaseed profiles                                  # the profiles and their versions
metaseed profile schema --profile miappe -v 1.2    # entity types and fields
metaseed dataset create test-drought --profile miappe -v 1.2
metaseed entity create test-drought Investigation --set unique_id=INV001 --set title="Drought trial"
metaseed dataset validate test-drought
metaseed dataset export test-drought --format dcat -o out/
metaseed ui                                        # the web interface
metaseed mcp --transport stdio                     # the MCP server, for Claude Desktop

Output is JSON, so a script reads what a person reads. The CLI reference lists every command; Capability parity records which command, MCP tool, and web route serve each capability.

Python

from metaseed import MetaseedClient

client = MetaseedClient("miappe", "1.2")

investigation = client.create_entity(
    "Investigation",
    {"unique_id": "INV001", "title": "Drought tolerance trial"},
)
client.create_entity(
    "Study",
    {"unique_id": "STU001", "title": "Field trial 2024", "start_date": "2024-03-01"},
    parent_id=investigation.id,
)

result = client.validate()
print(result.valid, [issue.message for issue in result.issues])

The Python API reference covers the client; the public API contract lists what is stable.

Web interface

metaseed ui serves the datasets overview, entity forms and tables, validation, the graph view, the profile explorer, the spec builder, and the Plugins page for the adapters.

MCP server

metaseed mcp exposes the same capabilities as tools for an AI agent: profile discovery, dataset and entity editing, extraction from source files, validation, ontology lookup, and specification authoring. See the MCP setup guide.

Validation

Rules are part of the profile, in YAML:

validation_rules:
  - name: study_unique_within_investigation
    type: uniqueness
    applies_to: [Study]
    field: unique_id
    unique_within: parent

  - name: observation_unit_names_a_study
    type: referential_integrity
    applies_to: [ObservationUnit]
    field: study_id
    reference: Study.unique_id

Rule types cover required fields, patterns, numeric and date ranges, coordinate pairs, uniqueness within a parent or globally, referential integrity, and conditions.

Architecture

graph LR
    subgraph interfaces["Interfaces"]
        direction RL
        CLI["CLI"]
        UI["Web interface"]
        MCP["MCP server"]
    end

    subgraph core["Core"]
        Client["MetaseedClient"]
        Facade["ProfileFacade"]
        Factory["Model factory"]
        Validators["Validation engine"]
    end

    subgraph data["Data"]
        Specs["YAML profiles"]
        Repo["Entity repository"]
        Storage["JSON and YAML files"]
    end

    interfaces --> Client
    Client --> Facade
    Facade --> Factory
    Facade --> Validators
    Factory --> Specs
    Validators --> Repo
    Repo --> Storage

The architecture overview describes each layer.

Development

make setup    # dependencies and pre-commit hooks
make dev      # the web interface with reload
make test     # the test suite
make lint     # ruff and mypy
make docs     # the documentation site with reload

The project follows document-driven and test-driven development: a change starts in docs/, gets a test, then an implementation. Rules are enforced by tests rather than by review; the contributing guide lists them.

Data sources and attribution

Ontology lookup and validation use the EMBL-EBI Ontology Lookup Service (OLS4). Term data comes from the public OLS4 API and stays the property of the source ontologies; use of OLS is subject to the EMBL-EBI terms of use. Metaseed caches results, limits its request rate, and identifies itself with a descriptive User-Agent. For bulk term resolution, download the source ontologies or run a local OLS instance instead of using the public API.

License

MIT

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