mosaic-mcp 1.0.0

Pre-clinical drug discovery intelligence — 28 MCP tools for targets, compounds, patents, clinical trials, and competitive landscapes

mosaic-mcp

Pre-clinical drug discovery intelligence as an MCP server. Query 300+ drug targets, 10K+ compounds, 35K+ papers, 18K+ clinical trials, and 12K+ patents through 28 specialized tools.

Quick Start

pip install mosaic-mcp

With Claude Desktop

Add to your claude_desktop_config.json:

{
  "mcpServers": {
    "mosaic": {
      "command": "mosaic-mcp",
      "env": {
        "DATABASE_URL": "postgresql://reader:[e-mail]/mosaic_db?sslmode=require"
      }
    }
  }
}

With Claude Code

claude mcp add mosaic -- mosaic-mcp

Standalone

export DATABASE_URL="postgresql://..."
export MOSAIC_API_KEY="msk_..."       # Optional — for Pro tools
mosaic-mcp                             # stdio transport (default)
mosaic-mcp --transport sse --port 3001 # SSE for remote clients

Tools

Free Tier (8 tools)

Tool	Description
mosaic_search_targets	Search drug targets by name, gene symbol, or keyword
mosaic_get_target_profile	Comprehensive target dossier (biology, compounds, scores)
mosaic_get_target_compounds	Compounds tested against a target with SAR data
mosaic_get_target_patents	Patent landscape for a target
mosaic_get_target_papers	Literature for a target
mosaic_kg_stats	Knowledge graph overview statistics
mosaic_list_indications	Available disease indications
mosaic_target_scores	Target attractiveness scoring

Pro Tier (20 additional tools)

Competitive landscape, pathway context, compound selectivity, indication landscape, target validation, clinical pipeline, compound analogs, target comparison, opportunity finding, organization portfolio, target network, mechanism of action, evidence maps, relation search, polypharmacology, clinical trial results, FDA regulatory status, drug comparison, drug repurposing candidates, and KOL discovery.

Data Coverage

Entity	Count
Drug Targets	347 (oncology + neuroscience + cardiovascular)
Compounds	10,831
Clinical Trials	18,324
Papers	35,430
Patents	12,603
Indications	15,013
Organizations	45,496

Configuration

Variable	Required	Description
DATABASE_URL	Yes	PostgreSQL connection string (Neon hosted or self-hosted)
MOSAIC_API_KEY	No	API key for Pro tool access
MOSAIC_TIER	No	Override tier (free, pro, enterprise)

License

Apache 2.0 for the MCP server tools. The hosted knowledge graph data requires a subscription for Pro-tier access.