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mvTCR: A multimodal generative model to learn a unified representation across TCR sequences and scRNAseq data for joint analysis of single-cell immune profiling data

Project description

mvTCR

mvTCR is a multimodal generative model to learn a unified representation across across TCR sequences and scRNAseq data and datasets for joint analysis of single-cell immune profiling data.

  • The publication can be found here
  • GitHub can be found here

Installation

To install mvTCR follow these steps:

  1. Create a conda environment: conda create -n mvTCR python=3.10
  2. Install mvTCR pip install mvTCR
  3. Install PyTorch e.g. v2.1.2 with the appropriate CUDA version

Tutorial

Please have a look at our tutorial notebooks found here.

Bugs and Errors

If you find any bugs or run into errors please report them to our GitHub.

Reproducibility

The reproducibility GitHub features experiments and code used in the publication. If you want to reproduce them, please use mvTCR v0.1.3 together with PyTorch v1.8.0 .

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