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Nexotype MCP Server

AI-powered biomedical knowledge graph for drug discovery, genomics, and market intelligence.

Connect your AI tools to the Nexotype platform and query the biomedical knowledge graph through conversation.

Installation

pip install nexotype-mcp

Or with uv:

# Install uv (if not already installed)
brew install uv

# Add uv tools to PATH (one-time setup)
echo 'export PATH="$HOME/.local/bin:$PATH"' >> ~/.zshrc
source ~/.zshrc

# Install nexotype-mcp
uv tool install nexotype-mcp

Already installed? Update:

pip install --upgrade nexotype-mcp
# or
uv tool upgrade nexotype-mcp

Authentication

nexotype-cli login

Enter your email and password. Credentials are stored securely at ~/.nexotype/credentials.json (chmod 600).

Configure Your AI Client

Claude Desktop

Edit ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows):

{
  "mcpServers": {
    "nexotype": {
      "command": "nexotype-mcp"
    }
  }
}

Claude Code

claude mcp add nexotype -- nexotype-mcp

VS Code / Cursor

Add to your MCP settings:

{
  "nexotype": {
    "command": "nexotype-mcp"
  }
}

Restart the application after saving.

Tools (28)

Graph Intelligence (6 tools)

Tool Description
explore_network N-hop neighborhood of any entity
find_path Shortest path between two entities
find_similar Entities sharing the most relationships
company_deep_dive Full portfolio of a pharma/biotech company
drug_discovery Targets, pathways, indications for a drug
competitive_landscape All drugs and companies targeting a protein

AI Query (1 tool)

Tool Description
ask_knowledge_graph Natural language question → grounded answer from graph

Search & Browse (2 tools)

Tool Description
search_entities List entities of any of the 61 types
get_entity Full details for a specific entity

Context (3 tools)

Tool Description
get_permissions Check subscription tier and domain access
list_subjects List available biological subjects
set_subject Set active subject for personalization tools

Personalized Health (10 tools)

Tool Description
get_user_profile Personal info linked to the subject
list_user_variants Detected genomic variants
list_biomarker_readings Time-series health data
create_biomarker_reading Log a new biomarker measurement
list_treatment_logs Intervention history
create_treatment_log Log a new treatment
list_pathway_scores Pathway health scores
list_recommendations Personalized treatment suggestions
upload_genomic_file Upload VCF/23andMe file for analysis
get_processing_status Check genomic file processing progress

Commercial Intelligence (6 tools)

Tool Description
list_market_organizations Pharma/biotech companies
get_market_organization Full company details
list_patents Patent filings and status
list_development_pipelines Clinical trial phases
list_regulatory_approvals FDA/EMA approvals
list_licensing_agreements Commercial partnerships

Example Queries

"What drugs target EGFR and are in Phase III?"
"Show me Novo Nordisk's full portfolio"
"What variants are associated with Alzheimer's risk?"
"Compare GLP-1 receptor agonists across companies"
"Who else is targeting mTOR?"
"List all therapeutic peptides in the database"
"What are my detected genomic variants?"

CLI Commands

Command Description
nexotype-cli login Authenticate via browser (OAuth device flow)
nexotype-cli login --basic Authenticate with email/password (headless fallback)
nexotype-cli logout Delete stored credentials
nexotype-cli status Show current auth status

Environment Variables

Variable Default Description
NEXOTYPE_API_URL http://localhost:8000 API server URL

Download files

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Source Distribution

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