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Standalone HTTP ToolServer for OmniBioAI (REST-backed bioinformatics tools like Enrichr)

Project description

omnibioai-toolserver

A standalone HTTP ToolServer for the OmniBioAI ecosystem.

This service implements the REST contract expected by omnibioai-tool-exec’s HttpToolServerAdapter, enabling secure, validated, and reproducible execution of REST-backed bioinformatics tools (e.g. Enrichr, annotation services, external APIs).

It is designed to run independently and be registered as a remote execution server in OmniBioAI TES.


Implemented API Contract

The ToolServer exposes the following endpoints:

  • GET /capabilities Advertise supported tools, engines, resources, and runtime policies.

  • POST /validate Validate tool inputs and resource requests.

  • POST /runs Submit a tool execution request.

  • GET /runs/{id} Retrieve run state (QUEUED, RUNNING, COMPLETED, FAILED).

  • GET /runs/{id}/logs Retrieve execution logs.

  • GET /runs/{id}/results Retrieve structured tool results once the run is completed.

This contract matches the expectations of omnibioai-tool-execHttpToolServerAdapter.


Current Capabilities

  • Engine: http_toolserver

  • Tools:

    • enrichr_pathway — Pathway enrichment via Enrichr (REST, multipart-safe)
  • Execution model:

    • Stateless REST calls
    • Structured validation
    • Run lifecycle tracking
  • Designed for:

    • OmniBioAI agents
    • TES-controlled execution
    • Future multi-tool expansion (OMIM, GO, UniProt, etc.)

Running the ToolServer

Requirements

  • Python ≥ 3.11

Install

pip install -r requirements.txt

Run

uvicorn toolserver_app:create_app --factory --host 0.0.0.0 --port 9090

Verify

curl http://127.0.0.1:9090/capabilities | python -m json.tool

Integration with OmniBioAI TES

Register this service as a server in omnibioai-tool-exec:

- server_id: enrichment_remote
  display_name: Enrichment ToolServer
  adapter_type: http_toolserver
  config:
    base_url: "http://127.0.0.1:9090"

Then submit runs through TES:

POST /api/runs/submit

The ToolServer is never called directly by the browser or LLM—all execution is mediated by TES.


Adding a New REST-Backed Tool

  1. Create a new handler:
toolserver/tools/<new_tool>.py

Implement:

def _validate(inputs, resources) -> {
  "ok": bool,
  "errors": [],
  "warnings": []
}

def _run(inputs, resources, log) -> Dict[str, Any]
  1. Register the tool in:
toolserver/tools/__init__.py
registry.register(ToolHandler(...))
  1. Restart the server.

The tool will be automatically advertised via /capabilities.

No changes are required in TES beyond refreshing server capabilities.


Design Principles

  • LLMs never execute tools directly

  • All execution is validated and audited

  • Strict separation between:

    • intent (agents / UI)
    • orchestration (TES)
    • execution (ToolServer)
  • REST-first, container-friendly, and infrastructure-agnostic


Status

  • Frozen initial release
  • Enrichr pathway enrichment working end-to-end with TES
  • Stable API contract

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