opennano 0.1.2

A Python package for processing NanoString GeoMx data.

Open Nano

Open Nano is a free open-source python package developed to address a lack of Python-based tools for analyzing Nanostring GeoMx DSP data.

From your dcc, pkc, and metadata files, you can:

• create an AnnData object of your data
• perform quality control and normalization steps
• do a differential gene expression analysis
• look at spatial autocorrelation with Moran's I statistic
• perform UMAP and tSNE clustering

Benchmarked against GeoMxTools R package and DESeq2.

See

Created by Charalampos Anagnostakis, Laura Beltrame, Cristiano Cordì, and Niamh Callian Keenan as part of the Integrated Bioinformatics Project for the MSc in Bioinformatics at KU Leuven, Belgium