A phylogenetic networks analysis package
Project description
PhyloZoo is a Python package for working with phylogenetic networks and related evolutionary data types. PhyloZoo aims to provide the foundational infrastructure for phylogenetic network analysis in Python — a common framework that other packages can build on.
Key Features
- Directed & semi-directed networks — represent phylogenetic networks as fully directed rooted DAGs or as semi-directed/mixed graphs that allow root uncertainty. Both representations are validated on construction to guarantee well-formed phylogenetic objects. Includes a rich library of operations: network classifications, generators, conversions between representations, and much more.
- Quartets, splits & distance matrices — support for quartet systems, split systems, and pairwise distance matrices: the core building blocks for phylogenetic inference and comparison.
- Multiple sequence alignments — store and manipulate sequence data with efficient NumPy-backed arrays, including bootstrapping and site-pattern extraction.
- Flexible visualization — plot networks with different layouts and fine-grained control over styling, labels, and coloring via Matplotlib.
- Standard file formats — read and write common phylogenetic formats including eNewick, DOT, FASTA, and NEXUS, making it easy to integrate with existing workflows.
- Performance — leverages NumPy and optional Numba JIT compilation for computationally intensive algorithms.
Installation
To install the recommended version that includes vizualization, do:
pip install phylozoo[viz]
Documentation
For detailed documentation, installation instructions, tutorials, and API reference, visit the PhyloZoo docs.
Citation
If you use PhyloZoo in your research, please cite:
Niels Holtgrefe (2026). PhyloZoo. Available at: https://github.com/nholtgrefe/phylozoo
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