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Open-source Python library for AASM 2.6-compliant automated polysomnography scoring

Project description

psgscoring

Open-source AASM 2.6–compliant respiratory scoring for polysomnography.

PyPI Python License Tests

Paper

Rombaut B, Rombaut B, Rombaut C, et al. Automated Polysomnography Scoring for Clinical Sleep Medicine: An Open-Source Platform Validated Against 59 Independent Scorer Sessions on PSG-IPA. Manuscript in preparation, 2026.

Technical details (signal processing chain, classification logic, all twelve bias corrections): Technical Reference (Online Supplement)

What this library does

psgscoring detects and classifies respiratory events (apneas, hypopneas, RERAs) in polysomnography recordings following AASM 2.6 rules. It extends YASA (Vallat & Walker, eLife 2021) from sleep staging into a complete clinical respiratory scoring pipeline.

Three contributions that distinguish this library:

  1. Twelve bias corrections — the first systematic identification and empirical quantification of six over-counting and six under-counting mechanisms in automated respiratory scoring
  2. AHI confidence interval — every study is scored at three stringency levels (strict/standard/sensitive), yielding a per-study robustness grade (A/B/C) rather than a single AHI number
  3. Clinical auditability — every event carries a confidence score, classification rule index, and per-correction counters, enabling the reviewing physician to verify individual scoring decisions

Installation

pip install psgscoring

Requirements: Python ≥3.9, numpy, scipy, mne. No GPU required.

Quick Start

import mne
from psgscoring import run_pneumo_analysis

# Load EDF and provide a hypnogram (e.g., from YASA)
raw = mne.io.read_raw_edf("recording.edf", preload=True)
hypnogram = ["W", "N1", "N2", "N2", "N3", ...]  # per 30-s epoch

# Run the full pipeline
results = run_pneumo_analysis(raw, hypnogram, scoring_profile="standard")

# Access results
resp = results["respiratory"]["summary"]
print(f"AHI: {resp['ahi_total']}, Severity: {resp['severity']}")
print(f"Events: {resp['n_obstructive']} OA, {resp['n_hypopnea']} Hyp")

# AHI confidence interval
interval = results["interval"]
print(f"AHI interval: [{interval['strict']['ahi']}{interval['sensitive']['ahi']}]")
print(f"Robustness: {interval['robustness_grade']}")

Scoring Profiles

Parameter Strict Standard Sensitive
Hypopnea threshold ≥30% ≥30% ≥25%
SpO₂ nadir window 30 s 45 s 45 s
Peak-based detection No Yes Yes

Validation

PSG-IPA (PhysioNet): 5 recordings, 59 independent scorer sessions. Mean |ΔAHI| = 2.0/h, severity concordance 4/5. See the paper for full results.

PSG-Audio (Sismanoglio Hospital, Athens): n=194, open access. External validation in progress.

Twelve Bias Corrections

# Correction Direction Clinical impact
1 Post-apnea baseline inflation Over-counting Prevents false Mild→Moderate
2 SpO₂ cross-contamination Over-counting Flags uncertain coupling
3 Cheyne-Stokes trough scoring Over-counting Prevents HF misdiagnosis as OSA
4 Low-confidence defaults Over-counting Confidence stratification
5 Artefact-flank exclusion Over-counting Prevents post-disconnect events
6 Local baseline validation Over-counting Rejects inflated-baseline FPs
7 Peak-based amplitude detection Under-counting AASM-conformant breath-level
8 Extended SpO₂ nadir window Under-counting Catches delayed desaturations
9 Flow smoothing removal Under-counting Eliminated +54 FPs on PSG-IPA
10 Position signal auto-mapping Under-counting Handles raw ADC encoding
11 Configurable profiles Under-counting Sensitivity adjustment per study
12 Flattening-based RERA Under-counting Flow limitation without amplitude drop

Architecture

~8,000 lines across 18 submodules, 98 unit tests (CI: Python 3.9–3.12):

constants · utils · signal · breath · classify · spo2 · plm · ancillary · respiratory · pipeline · pipeline_profiles · profiles · postprocess · signal_quality · signal_quality_channels · ecg_effort · _types

Related

  • YASAFlaskified — web platform integrating psgscoring with YASA staging, multilingual PDF reports, EDF+ export, and FHIR R4
  • YASA — AI-based sleep staging (Vallat & Walker, eLife 2021)
  • slaapkliniek.be — live instance (no installation required)

Citation

@article{rombaut2026psgscoring,
  title     = {Automated Polysomnography Scoring for Clinical Sleep Medicine:
               An Open-Source Platform Validated Against 59 Independent
               Scorer Sessions on {PSG-IPA}},
  author    = {Rombaut, Bart and Rombaut, Briek and Rombaut, Cedric},
  year      = {2026},
  note      = {Manuscript in preparation}
}

Disclaimer

psgscoring is research software — not a medical device. It is not CE-marked (MDR 2017/745) or FDA-cleared. All outputs are research-grade estimates that must be reviewed by a qualified clinician before any diagnostic or therapeutic decision. See DISCLAIMER.md for the full text.

License

BSD-3-Clause. See LICENSE.


Developed at Slaapkliniek AZORG, Aalst, Belgium. Contact: bart.rombaut@azorg.be

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