pyopencl

PyOpenCL lets you access GPUs and other massively parallel compute devices from Python. It tries to offer computing goodness in the spirit of its sister project PyCUDA:

Object cleanup tied to lifetime of objects. This idiom, often called RAII in C++, makes it much easier to write correct, leak- and crash-free code.
Completeness. PyOpenCL puts the full power of OpenCL’s API at your disposal, if you wish. Every obscure get_info() query and all CL calls are accessible.
Automatic Error Checking. All CL errors are automatically translated into Python exceptions.
Speed. PyOpenCL’s base layer is written in C++, so all the niceties above are virtually free.
Helpful and complete Documentation as well as a Wiki.
Liberal license. PyOpenCL is open-source under the MIT license and free for commercial, academic, and private use.
Broad support. PyOpenCL was tested and works with Apple’s, AMD’s, and Nvidia’s CL implementations.

What you’ll need:

gcc/g++ at or newer than version 4.8.2 and binutils at or newer than 2.23.52.0.1-10 (CentOS version number). On Windows, use the mingwpy compilers.
numpy, and
an OpenCL implementation. (See this howto for how to get one.)

Places on the web related to PyOpenCL: