pypulseqpp

pypulseqpp is a fast drop-in replacement for PyPulseq, written in Python with a C++ backend. You write MR pulse sequences exactly as you write them in PyPulseq, and get back a sequence that is fast to build, check and write, however long it is. Change one line of your script,

import pypulseqpp as pp  # in place of: import pypulseq as pp

and it runs: the event factories, Opts and the Sequence methods keep PyPulseq's names, arguments and units. Underneath, the sequence is stored by a C++ core, so a scan of a million blocks is built, deduplicated and written in seconds.

You write the sequence; pypulseqpp does the rest. It stores and deduplicates your events, writes Pulseq text and binary files that any Pulseq interpreter plays, and checks the result against your scanner: timing, gradient amplitude and slew rate, peripheral nerve stimulation, mechanical resonances, acoustic noise and SAR.

pypulseqpp architecture

How it works

A Pulseq sequence is a list of blocks played back to back, and each block holds at most one event per channel: an RF pulse, a gradient on each axis, an ADC window, a delay. You build it in five steps:

Describe your scanner: field strength, gradient amplitude and slew-rate limits, raster times and dead times. This is the system object, a pp.Opts.
Design the events with the factories (pp.make_sinc_pulse, pp.make_trapezoid, pp.make_adc...). Each one is solved against system, so a gradient you ask for by its area comes back as the shortest trapezoid your hardware plays.
Add the events to the sequence block by block, in a loop over the lines of k-space.
Check it. seq.check_timing() checks every block against the rasters and dead times; the gradient, PNS, mechanical-resonance and SAR checks look at the whole scan.
Write the .seq file, and play it on the scanner through your vendor's Pulseq interpreter.

Here is a 2D gradient echo, written the PyPulseq way:

import numpy as np

import pypulseqpp as pp

system = pp.Opts(max_grad=32, grad_unit="mT/m", max_slew=130, slew_unit="T/m/s")
fov, n = 256e-3, 64

rf, gz, gz_reph = pp.make_sinc_pulse(
    flip_angle=np.deg2rad(15),
    duration=2e-3,
    slice_thickness=5e-3,
    time_bw_product=4,
    system=system,
    return_gz=True,
)
gx = pp.make_trapezoid("x", flat_area=n / fov, flat_time=3.2e-3, system=system)
adc = pp.make_adc(n, duration=gx.flat_time, delay=gx.rise_time, system=system)
gx_pre = pp.make_trapezoid("x", area=-gx.area / 2, duration=1e-3, system=system)

seq = pp.Sequence(system)
for line in range(n):
    gy_pre = pp.make_trapezoid(
        "y", area=(line - n / 2) / fov, duration=1e-3, system=system
    )
    seq.add_block(rf, gz)
    seq.add_block(gx_pre, gy_pre, gz_reph)
    seq.add_block(gx, adc)
    seq.add_block(pp.make_delay(10e-3))

ok, errors = seq.check_timing()
seq.write("gre.seq")

Sequences as functions

A script designs one protocol. Put the same code in a function of system and keyword arguments, and it designs any protocol you ask for:

def gre(system, *, fov=256e-3, n=64, flip_angle_deg=15.0) -> pp.Sequence:
    ...
    return seq

The keyword arguments are your protocol. Document each in a NumPy-style Parameters section, with its unit, and pp.cli.run(gre) turns them into a command line.
Return the sequence, or a list of sequences when the scan has prescans; the main sequence goes last.
This is the shape pulserver expects, so the same function becomes a sequence the operator edits in the scanner UI.

pypulseqpp ships 28 sequences written this way (gradient echo, spin echo, FSE, MPRAGE, bSSFP, EPI, ZTE, with Cartesian, radial, spiral and PROPELLER readouts), each one a module you can call or run from the command line:

from pypulseqpp import sequences

seq = sequences.gre2D_sequence(n_x=64, n_y=64)

python -m pypulseqpp.sequences.sequence.gre2D_sequence --help

They are built from sequence modules, ready-made excitations, preparations and readouts that you can reuse in your own functions.

The checks compute estimates. Passing them does not establish scanner or patient safety.

Installation

pip install pypulseqpp

Wheels are published for Linux x86-64, macOS (Apple silicon and x86-64) and Windows AMD64, Python 3.10 to 3.14.

Learn more

Course: ten lessons from a pulse-acquire experiment to your own sequence module.
Sequence catalogue: every shipped sequence, with its protocol and diagram.
From a PyPulseq script: your script, and the same script as a sequence function.
Documentation, for every option and API detail.

How to cite

pypulseqpp has no publication of its own. If you use it, please cite Pulseq and PyPulseq:

@article{layton2017pulseq,
  title   = {Pulseq: a rapid and hardware-independent pulse sequence prototyping framework},
  author  = {Layton, Kelvin J and Kroboth, Stefan and Jia, Feng and Littin, Sebastian
             and Yu, Huijun and Leupold, Jochen and Nielsen, Jon-Fredrik
             and St{\"o}cker, Tony and Zaitsev, Maxim},
  journal = {Magnetic Resonance in Medicine},
  volume  = {77},
  number  = {4},
  pages   = {1544--1552},
  year    = {2017},
  doi     = {10.1002/mrm.26235}
}

@article{ravi2019pypulseq,
  title   = {PyPulseq: A Python Package for MRI Pulse Sequence Design},
  author  = {Ravi, Keerthi Sravan and Geethanath, Sairam and Vaughan, John Thomas},
  journal = {Journal of Open Source Software},
  volume  = {4},
  number  = {42},
  pages   = {1725},
  year    = {2019},
  doi     = {10.21105/joss.01725}
}

License

MIT, except bundled or vendored third-party components, which keep their own licences. See License and third-party notices.

Metadata

Release files for pypulseqpp 0.0.39

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Source distribution (sdist)

Source distribution for pypulseqpp 0.0.39
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pypulseqpp-0.0.39.tar.gz	1.7 MB	Oct 12, 2026	Details

Built distributions (wheels)

Table of built distributions (wheels) for pypulseqpp 0.0.39
File	Interpreter	ABI	Platform	Reset
pypulseqpp-0.0.39-cp314-cp314-win_amd64.whl 1.4 MB Oct 12, 2026	CPython 3.14	CPython 3.14	Windows x86-64	Details
pypulseqpp-0.0.39-cp314-cp314-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.14	CPython 3.14	Linux glibc 2.27+ x86-64, Linux glibc 2.28+ x86-64	Details
pypulseqpp-0.0.39-cp314-cp314-macosx_11_0_arm64.whl 1.2 MB Oct 12, 2026	CPython 3.14	CPython 3.14	macOS 11.0+ ARM64	Details
pypulseqpp-0.0.39-cp314-cp314-macosx_10_15_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.14	CPython 3.14	macOS 10.15+ x86-64	Details
pypulseqpp-0.0.39-cp313-cp313-win_amd64.whl 1.4 MB Oct 12, 2026	CPython 3.13	CPython 3.13	Windows x86-64	Details
pypulseqpp-0.0.39-cp313-cp313-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.13	CPython 3.13	Linux glibc 2.27+ x86-64, Linux glibc 2.28+ x86-64	Details
pypulseqpp-0.0.39-cp313-cp313-macosx_11_0_arm64.whl 1.2 MB Oct 12, 2026	CPython 3.13	CPython 3.13	macOS 11.0+ ARM64	Details
pypulseqpp-0.0.39-cp313-cp313-macosx_10_13_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.13	CPython 3.13	macOS 10.13+ x86-64	Details
pypulseqpp-0.0.39-cp312-cp312-win_amd64.whl 1.4 MB Oct 12, 2026	CPython 3.12	CPython 3.12	Windows x86-64	Details
pypulseqpp-0.0.39-cp312-cp312-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.12	CPython 3.12	Linux glibc 2.27+ x86-64, Linux glibc 2.28+ x86-64	Details
pypulseqpp-0.0.39-cp312-cp312-macosx_11_0_arm64.whl 1.2 MB Oct 12, 2026	CPython 3.12	CPython 3.12	macOS 11.0+ ARM64	Details
pypulseqpp-0.0.39-cp312-cp312-macosx_10_13_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.12	CPython 3.12	macOS 10.13+ x86-64	Details
pypulseqpp-0.0.39-cp311-cp311-win_amd64.whl 1.4 MB Oct 12, 2026	CPython 3.11	CPython 3.11	Windows x86-64	Details
pypulseqpp-0.0.39-cp311-cp311-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.11	CPython 3.11	Linux glibc 2.27+ x86-64, Linux glibc 2.28+ x86-64	Details
pypulseqpp-0.0.39-cp311-cp311-macosx_11_0_arm64.whl 1.2 MB Oct 12, 2026	CPython 3.11	CPython 3.11	macOS 11.0+ ARM64	Details
pypulseqpp-0.0.39-cp311-cp311-macosx_10_9_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.11	CPython 3.11	macOS 10.9+ x86-64	Details
pypulseqpp-0.0.39-cp310-cp310-win_amd64.whl 1.4 MB Oct 12, 2026	CPython 3.10	CPython 3.10	Windows x86-64	Details
pypulseqpp-0.0.39-cp310-cp310-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.10	CPython 3.10	Linux glibc 2.28+ x86-64, Linux glibc 2.27+ x86-64	Details
pypulseqpp-0.0.39-cp310-cp310-macosx_11_0_arm64.whl 1.2 MB Oct 12, 2026	CPython 3.10	CPython 3.10	macOS 11.0+ ARM64	Details
pypulseqpp-0.0.39-cp310-cp310-macosx_10_9_x86_64.whl 1.3 MB Oct 12, 2026	CPython 3.10	CPython 3.10	macOS 10.9+ x86-64	Details

Total release size: 27.3 MB

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Artifact

Subject: pypulseqpp-0.0.39-cp313-cp313-macosx_10_13_x86_64.whl
SHA-256 checksum: 325703e5362058779f95510dc0a5137d1c6771019e539d50d30fe3b3d1f7efd6 Verifying attestations

Release files / pypulseqpp-0.0.39-cp312-cp312-win_amd64.whl

Download URL	pypulseqpp-0.0.39-cp312-cp312-win_amd64.whl
Size	1.4 MB
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

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Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp312-cp312-win_amd64.whl
SHA-256 checksum: eedeeb0de021a70bdcab1f68943dbb4099b2af575ac1875f7be56c13054102cc Verifying attestations

Release files / pypulseqpp-0.0.39-cp312-cp312-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl

Download URL	pypulseqpp-0.0.39-cp312-cp312-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

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Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp312-cp312-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl
SHA-256 checksum: a04a17656dccd62928cf4c0f280576877cd484199c8319a753a1207d0a3c66a3 Verifying attestations

Release files / pypulseqpp-0.0.39-cp312-cp312-macosx_11_0_arm64.whl

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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

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Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp312-cp312-macosx_11_0_arm64.whl
SHA-256 checksum: be099772d083d1f8919a27cfc1e253a7780f39f405df4f91d9042bd32f247cb1 Verifying attestations

Release files / pypulseqpp-0.0.39-cp312-cp312-macosx_10_13_x86_64.whl

Download URL	pypulseqpp-0.0.39-cp312-cp312-macosx_10_13_x86_64.whl
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

Publishing configuration: github.com/pulserver/pypulseqpp/blob/bd263eb1d93b7a53750a6d494f84c75e422169f8/.github/workflows/tags-release.yml
Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp312-cp312-macosx_10_13_x86_64.whl
SHA-256 checksum: a309aa06216c03ed05c62752bfad0de726113958107815aaee3d28157b3506ac Verifying attestations

Release files / pypulseqpp-0.0.39-cp311-cp311-win_amd64.whl

Download URL	pypulseqpp-0.0.39-cp311-cp311-win_amd64.whl
Size	1.4 MB
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

Publishing configuration: github.com/pulserver/pypulseqpp/blob/bd263eb1d93b7a53750a6d494f84c75e422169f8/.github/workflows/tags-release.yml
Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp311-cp311-win_amd64.whl
SHA-256 checksum: a423cdcbe83471c5eaf5ff1f55be675df80cd79a1b688b5b69f98181eb864bcc Verifying attestations

Release files / pypulseqpp-0.0.39-cp311-cp311-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl

Download URL	pypulseqpp-0.0.39-cp311-cp311-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

Publishing configuration: github.com/pulserver/pypulseqpp/blob/bd263eb1d93b7a53750a6d494f84c75e422169f8/.github/workflows/tags-release.yml
Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp311-cp311-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl
SHA-256 checksum: de32abe1272431ec244ced57a51f17b357a5fcc5a25de3c98cac885cae6a4505 Verifying attestations

Release files / pypulseqpp-0.0.39-cp311-cp311-macosx_11_0_arm64.whl

Download URL	pypulseqpp-0.0.39-cp311-cp311-macosx_11_0_arm64.whl
Size	1.2 MB
Tags	CPython 3.11 macOS 11.0+ ARM64
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

Publishing configuration: github.com/pulserver/pypulseqpp/blob/bd263eb1d93b7a53750a6d494f84c75e422169f8/.github/workflows/tags-release.yml
Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp311-cp311-macosx_11_0_arm64.whl
SHA-256 checksum: bcd0d9f9cb0ba03148813015d823195a0bca560cf63d4c357e273936e2dee0ee Verifying attestations

Release files / pypulseqpp-0.0.39-cp311-cp311-macosx_10_9_x86_64.whl

Download URL	pypulseqpp-0.0.39-cp311-cp311-macosx_10_9_x86_64.whl
Size	1.3 MB
Tags	CPython 3.11 macOS 10.9+ x86-64
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

Publishing configuration: github.com/pulserver/pypulseqpp/blob/bd263eb1d93b7a53750a6d494f84c75e422169f8/.github/workflows/tags-release.yml
Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp311-cp311-macosx_10_9_x86_64.whl
SHA-256 checksum: 3232e2d6ad99ffab6c1ce8c97062127d8477224193d316b6ee5f4d39dbfa9de4 Verifying attestations

Release files / pypulseqpp-0.0.39-cp310-cp310-win_amd64.whl

Download URL	pypulseqpp-0.0.39-cp310-cp310-win_amd64.whl
Size	1.4 MB
Tags	CPython 3.10 Windows x86-64
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

Publishing configuration: github.com/pulserver/pypulseqpp/blob/bd263eb1d93b7a53750a6d494f84c75e422169f8/.github/workflows/tags-release.yml
Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp310-cp310-win_amd64.whl
SHA-256 checksum: c36d9eb29d2b465e941916339a1a6f4e422b81bf52b66cde4866a9308db09cc7 Verifying attestations

Release files / pypulseqpp-0.0.39-cp310-cp310-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl

Download URL	pypulseqpp-0.0.39-cp310-cp310-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl
Size	1.3 MB
Tags	CPython 3.10 Linux glibc 2.27+ x86-64 Linux glibc 2.28+ x86-64
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

Publishing configuration: github.com/pulserver/pypulseqpp/blob/bd263eb1d93b7a53750a6d494f84c75e422169f8/.github/workflows/tags-release.yml
Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp310-cp310-manylinux_2_27_x86_64.manylinux_2_28_x86_64.whl
SHA-256 checksum: 4c62729f797ce7dc974dfbd52005134ae2521ed32b13ec79dfc64d9931a2c8f0 Verifying attestations

Release files / pypulseqpp-0.0.39-cp310-cp310-macosx_11_0_arm64.whl

Download URL	pypulseqpp-0.0.39-cp310-cp310-macosx_11_0_arm64.whl
Size	1.2 MB
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

Publishing configuration: github.com/pulserver/pypulseqpp/blob/bd263eb1d93b7a53750a6d494f84c75e422169f8/.github/workflows/tags-release.yml
Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp310-cp310-macosx_11_0_arm64.whl
SHA-256 checksum: b9ca51809c80cae4473557113095b2cf176865005d7686efe3f9af4c8751028b Verifying attestations

Release files / pypulseqpp-0.0.39-cp310-cp310-macosx_10_9_x86_64.whl

Download URL	pypulseqpp-0.0.39-cp310-cp310-macosx_10_9_x86_64.whl
Size	1.3 MB
Tags	CPython 3.10 macOS 10.9+ x86-64
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Upload date	Oct 12, 2026
Uploaded using Trusted Publishing? What is trusted publishing?	Yes
Uploaded via	`twine/7.0.0 CPython/3.13.14`

Provenance

Identity

Publishing platform: GitHub Actions
Publishing repository: github.com/pulserver/pypulseqpp
Publishing commit: github.com/pulserver/pypulseqpp/tree/bd263eb1d93b7a53750a6d494f84c75e422169f8

Workflow

Publishing configuration: github.com/pulserver/pypulseqpp/blob/bd263eb1d93b7a53750a6d494f84c75e422169f8/.github/workflows/tags-release.yml
Publishing logs: github.com/pulserver/pypulseqpp/actions/runs/38248469032/attempts/1

Artifact

Subject: pypulseqpp-0.0.39-cp310-cp310-macosx_10_9_x86_64.whl
SHA-256 checksum: 955c2f5f36914878368b60d8788f583e3db8991e1bd7c3eadf889a3b0ca88857 Verifying attestations