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A collection of tools for various bioinformatics tasks.

Project description

A collection of tools for various bioinformatics tasks.

Documentation

https://python-bioinformagicks.readthedocs.io

Features

Tools:

  • TF-IDF marker gene testing (“quickMarkers”), as in SoupX

  • JASMINE gene set scoring, as in Noureen et al.

  • Over-representation analyses (ORAs) with gProfiler

  • Cell mask generation based on geometric sketching, as in Geosketch

  • Cell mask generation based on embedding (i.e. UMAP) coordinate bounds

  • Z-standard scaling of gene expression on a per-group basis

Plotting:

  • Split embedding plots based on categorical observations

  • Stacked barplot generation of cell proportions split by group and counts normalized per-batch

Utilities:

  • Identification of genes often left ignored, like AW146154

  • Combination of categorical columns maintaining specified ordering

Credits

This package was created by Sylvia N. Michki.

This package was created with Cookiecutter and the audreyr/cookiecutter-pypackage project template.

License

Free software: GNU General Public License v3

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